Mohammad-Mehdi Khani | Tissue Engineering | Best Researcher Award

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Assoc. Prof. Dr. Mohammad-Mehdi Khani | Tissue Engineering | Best Researcher Award

Shahid Beheshti University of Medical Sciences | Iran

Assoc. Prof. Dr. Mohammad-Mehdi Khani, Associate Professor at the Department of Tissue Engineering and Applied Cell Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran, demonstrates exceptional expertise in biomechanics, tissue engineering, and regenerative medicine. With a Ph.D. in Biomedical Engineering (Biomechanics) from Amir-Kabir University of Technology, he has produced 61 publications with 767 citations and an h-index of 16, reflecting his significant scholarly impact. His research spans cell mechanics, mechanobiology, stem cell engineering, functional tissue engineering, cardiovascular and corneal regeneration, and regenerative medicine, bridging fundamental science with translational applications. Assoc. Prof. Dr. Mohammad-Mehdi Khani’s notable achievements include membership in Iran’s National Elites Foundation, recognition as a talented graduate, and the Nightingale Award for the best paper in Medical and Biological Engineering and Computing (2021). His work encompasses advanced studies on hydrogel-derived matrices, nanofibrous cardiac patches, stem cell differentiation, bioreactor cultivation, and computational modeling, significantly contributing to the understanding and development of innovative therapeutic strategies in tissue repair and biomedical engineering.

Profile: Scopus| Orcid | Google Scholar

Featured Publications

Moradi, S. L., Golchin, A., Hajishafieeha, Z., Khani, M. M., & Ardeshirylajimi, A. (2018). Bone tissue engineering: Adult stem cells in combination with electrospun nanofibrous scaffolds. Journal of Cellular Physiology, 233(10), 6509–6522.

Abazari, M. F., Soleimanifar, F., Amini Faskhodi, M., Mansour, R. N., & Khani, M. M. (2020). Improved osteogenic differentiation of human induced pluripotent stem cells cultured on polyvinylidene fluoride/collagen/platelet‐rich plasma composite nanofibers. Journal of Cellular Physiology, 235(2), 1155–1164.

Abazari, M. F., Soleimanifar, F., Enderami, S. E., Nematzadeh, M., Nasiri, N., & Khani, M. M. (2019). Incorporated-bFGF polycaprolactone/polyvinylidene fluoride nanocomposite scaffold promotes human induced pluripotent stem cells osteogenic differentiation. Journal of Cellular Biochemistry, 120(10), 16750–16759.

Jouybar, A., Seyedjafari, E., Ardeshirylajimi, A., Zandi-Karimi, A., & Feizi, N. (2017). Enhanced skin regeneration by herbal extract-coated poly-L-lactic acid nanofibrous scaffold. Artificial Organs, 41(11), E296–E307.

Saffar, R. J., Razfar, M. R., Salimi, A. H., & Khani, M. M. (2009). Optimization of machining parameters to minimize tool deflection in the end milling operation using genetic algorithm. World Applied Sciences Journal, 6(1), 64–69.

Shubham Gupta | Transfusion Medicine | Young Scientist Award

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Dr. Shubham Gupta | Transfusion Medicine | Young Scientist Award

Dr. Shubham Gupta, Medanta, India

Dr. Shubham Gupta is a Senior Resident in Immunohematology & Transfusion Medicine at Medanta – The Medicity, Gurugram, Haryana. He completed his DNB in Immunohematology & Transfusion Medicine and MBBS from Major S.D. Singh Medical College, Farrukhabad. With expertise in therapeutic procedures like plasma exchange, leukapheresis, and CAR-T cell therapy, Dr. Gupta has contributed to several publications on transfusion medicine and hematology. He has presented at numerous national conferences and participated in webinars on oncology, hematology, and blood transfusion. He holds memberships with ISTM, BBTS, ISBT, and SPCTT. 🩸💉

Publication Profile

Scopus

Education

Dr. Shubham Gupta is an expert in Immunohematology & Transfusion Medicine, currently serving as a Senior Resident at Medanta – The Medicity, Gurugram, Haryana. He completed his DNB in Immunohematology & Transfusion Medicine from Medanta and his MBBS from Major S.D. Singh Medical College & Hospital, Farrukhabad, Uttar Pradesh. Dr. Gupta is registered with both the Medical Council of Uttar Pradesh and the Haryana Medical Council. His work focuses on cutting-edge therapies like plasma exchange, leukapheresis, and CAR-T cell therapy, contributing significantly to the field of transfusion medicine and hematology. 💉

Professional Experience

Dr. Shubham Gupta has gained diverse clinical experience over the years. From June 2017 to July 2018, he worked for a year in the Department of Ophthalmology and Emergency Services at Government Doon Medical College, Dehradun, Uttarakhand. He then pursued his DNB residency in Immunohematology & Transfusion Medicine at Medanta – The Medicity, Gurugram, from June 2019 to July 2022, further strengthening his expertise. Since August 2022, he has been serving as a Senior Resident in the same department at Medanta, specializing in advanced transfusion therapies and hematology techniques. 💉👨‍⚕️

Certificate Courses 🎓

Dr. Shubham Gupta has pursued several specialized certificate courses to enhance his expertise in the medical field. These include the ICMR Basic Course in Biomedical Research, the ICMR Basic Course in Vector-Borne Diseases for Health Professionals, and a Certificate Course in Patient Blood Management (PBM). He has also completed the Good Clinical Practice (GCP) Certificate Course. Additionally, Dr. Gupta is trained in LIFECODES SS-OHLA Typing on the LUMINEX Analyzer and holds a certification from the National HIV Curriculum, an AIDS Education and Training Center Program by the University of Washington. 📚💉

Academic Courses & Teaching 📚

Dr. Shubham Gupta has been actively involved in academic programs to foster excellence in medical education. He has participated in the Post-graduate (DNB) Teaching Program organized by the National Board of Examination (NBE). He also completed the Clinical Excellence Program for Medical Officers (M.O.) at Medanta – The Medicity, honing his clinical skills and knowledge. Additionally, Dr. Gupta is certified in the Bone Marrow Transplant (BMT) Nursing Specialty Course, further enhancing his expertise in hematology and stem cell transplantation. These academic courses reflect his commitment to ongoing education and professional development. 🎓

Research Focus 🔬

Dr. Shubham Gupta’s research primarily focuses on Hematopoietic Progenitor Cells (HPC), particularly their infusion and adverse reactions in patients undergoing stem cell therapies, as demonstrated in his work on real-world evidence of adverse reactions to thawed HPC infusion. This research aims to understand the safety and effectiveness of these therapies in clinical settings, contributing to transfusion medicine and hematology. His work is critical for improving bone marrow transplantation (BMT) and stem cell therapies. Dr. Gupta’s research also spans areas of patient blood management (PBM) and immune response in hematology. 🧬💉

Publication Top Notes

Real-World Evidence Data on Adverse Reactions to Infusion of Thawed Hematopoietic Progenitor Cells: Retrospective Analysis from a Single Center in India

Shouhong Wang | Regeneration | Best Researcher Award

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Assoc. Prof. Dr. Shouhong Wang | Regeneration | Best Researcher Award

Assoc. Prof. Dr. Shouhong Wang, chengdu institute of biology, China

Assoc. Prof. Dr. Shouhong Wang is a researcher focused on organ/tissue regeneration, with expertise in the use of frog models (Xenopus) to study thyroid hormone (T3) signaling in developmental and regenerative processes. He earned a PhD in Zoology from the Chengdu Institute of Biology and completed a postdoc at the NICHD, NIH. His research aims to advance human regeneration and improve quality of life through understanding organ regeneration. Dr. Wang has published extensively and presented at numerous international conferences. He is a member of the American Thyroid Association, Chinese Society for Cell Biology, and more. 🐸🔬📚

 

 

Publication Profile

Scopus

Academic Qualifications

Assoc. Prof. Dr. Shouhong Wang’s academic journey includes a Postdoctoral Fellowship in Molecular Morphogenesis at NICHD, National Institutes of Health (2019), where he studied the role of thyroid hormone (T3) signaling in tail regeneration under the supervision of Yun-Bo Shi. He earned his PhD in Developmental Biology from Chengdu Institute of Biology, Chinese Academy of Sciences (2016-2018), researching embryo development and gene regulation in Microhyla fissipes. Dr. Wang also holds an MSc in Zoology (2013-2015) from the same institute, focusing on frog tail development and apoptosis. He completed his BSc in Animal Sciences at Sichuan Agricultural University (2009-2013).

Awards & Grants

Assoc. Prof. Dr. Shouhong Wang has been recognized for his academic excellence throughout his career. He received a scholarship three times during his studies at Sichuan Agricultural University (2009-2013) and was honored as an Outstanding Graduate in 2013. In 2015, he earned the Outstanding Student Academic Oral Report award from the Chinese Herpetological Society and was named a Merit Student by the Chinese Academy of Sciences (2015-2016). Additionally, Dr. Wang received the Excellence Award in Science Popularization from the Chinese Society for Cell Biology in 2015-2016, acknowledging his contributions to scientific communication.

 

 

Teaching Experience

Assoc. Prof. Dr. Shouhong Wang has a strong background in teaching and mentoring. He has tutored high school students, helping them develop a deeper understanding of biology and related subjects. Additionally, Dr. Wang has shared his expertise at various training organizations and welfare centers for children, contributing to their educational development. His dedication to teaching extends beyond the classroom, as he strives to inspire young minds and foster a passion for science, ensuring the next generation is equipped with the knowledge and skills to thrive.

 

 

Research Focus

Assoc. Prof. Dr. Shouhong Wang’s research is centered on the mechanisms of organ and tissue regeneration, with the aim of improving human regeneration processes and quality of life. By utilizing model animals, particularly the frog system, Xenopus, Dr. Wang explores the role of thyroid hormone (T3) signaling in developmental regulation of organ regeneration. His work is focused on understanding how thyroid hormone influences regeneration and utilizing knockout animals to investigate its effects. Ultimately, this research could contribute to advancements in repairing and replacing damaged human organs and tissues.

 

 

Publication Top Notes

  • “Dose-dependent toxic effects of triclosan on Rana omeimontis larvae: Insights into potential implications for neurodegenerative diseases” (Chen et al., 2025) 🧪
  • “Thyroid hormone receptor- and stage-dependent transcriptome changes affect the initial period of Xenopus tropicalis tail regeneration” (Wang et al., 2024) 🧬
  • “Protein arginine methyltransferase 1 regulates mouse enteroendocrine cell development and homeostasis” (Peng et al., 2024) 🧫
  • “Simplifying Genotyping of Mutants from Genome Editing with a Parallel qPCR-Based iGenotype Index” (Fu et al., 2024) 🔬
  • “Thyroid hormone receptor knockout prevents the loss of Xenopus tail regeneration capacity at metamorphic climax” (Wang et al., 2023) 🦎
  • “Liver development during Xenopus tropicalis metamorphosis is controlled by T3-activation of WNT signaling” (Tanizaki et al., 2023) 🐸
  • “Comparative Analysis of Transcriptome Profiles Reveals Distinct and Organ-Dependent Genomic and Nongenomic Actions of Thyroid Hormone in Xenopus tropicalis Tadpoles” (Wang et al., 2023) 🌱
  • “Essential and subtype-dependent function of thyroid hormone receptors during Xenopus metamorphosis” (Shi et al., 2023) 📚
  • “Osteological development of a small and fast metamorphic frog, Microhyla fissipes” (Zhang et al., 2021) 🦴

 

Hadi Alizadeh | Cancer stem cells | Best Researcher Award

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Mr. Hadi Alizadeh | Cancer stem cells | Best Researcher Award

Graduate Master Student, Tarbiat Modares University, Iran

Mr. Hadi Alizadeh is a Master’s graduate in Molecular Genetics from Tarbiat Modares University, Tehran, with a thesis on AGPAT3 gene and cisplatin resistance in ovarian cancer cells. His research encompasses gene expression analysis, drug discovery, and epigenomic profiling, focusing on chemoresistance mechanisms in cancer. He has contributed to various publications and presented at international conferences. Skilled in PCR, RNA-seq, flow cytometry, and bioinformatics, he is proficient in machine learning and molecular dynamics. Hadi has been recognized for his academic excellence, ranking highly in national exams. He also has hands-on experience in medical genetics and as a teaching assistant. 🧬💉🔬

 

Publication Profile

Orcid

Education

Mr. Hadi Alizadeh completed his Master’s in Molecular Genetics at Tarbiat Modares University, Tehran, from October 2021 to November 2023, achieving an impressive average of 18.2/20. His thesis, titled “Introduction of AGPAT3 gene as a regulator of cisplatin resistance in A2780 ovarian cancer cell line,” was supervised by Dr. Soltani. Prior to this, he earned a Bachelor’s degree in Genetics from Islamic Azad University, North Tehran, from October 2016 to May 2020, with a strong academic performance, securing an average of 17.83/20. His solid educational background highlights his commitment to molecular genetics and cancer research. 📚🧬

 

Research Experience

Mr. Hadi Alizadeh’s research experience includes significant work in molecular genetics and cancer research. For his Master’s thesis, he explored AGPAT3 gene as a regulator of cisplatin resistance in ovarian cancer cells, performing RNA-seq and various functional assays like RT-qPCR, western blotting, and apoptosis assays, revealing AGPAT3’s role in survival and cell cycle arrest under cisplatin treatment. He also studied the synergistic effect of dendrosomal nano-curcumin (DNC) with cisplatin in reducing cisplatin resistance. Additionally, he worked on epigenomic profiling of oxaliplatin-resistant HCT116 colorectal cancer cells and drug discovery targeting mTORC1 signaling. 🧬💻

 

Honors & Awards 🏆🎓

Mr. Hadi Alizadeh has demonstrated exceptional academic achievements throughout his career. In 2021, he ranked 18th out of nearly 10,000 participants in the national entrance exam for medical genetics in the healthcare system, showcasing his expertise and dedication. Additionally, he secured the 25th position among approximately 7,000 candidates in the national entrance exam for a Master’s program in genetics. These prestigious rankings highlight his strong academic foundation and passion for genetics research, setting the stage for his future contributions to the field. 🌟📚

 

Professional Experience 💼🔬

Mr. Hadi Alizadeh has gained valuable hands-on experience in various research and clinical settings. As a volunteer at Imam Khomeini Hospital in Tehran, he collected samples and performed RNA extraction for various projects. In his role as an apprentice at the Cytogenetic Lab, he conducted karyotyping as part of clinical genetic analyses, gaining key insights into genetic disorders. Additionally, as a Genetic Laboratory Technician prior to his Master’s, Mr. Alizadeh contributed to the COVID-19 response by performing RNA extraction and real-time PCR on samples, further honing his technical expertise in molecular genetics. 🧬🔬

 

Research Focus

Mr. Hadi Alizadeh’s research primarily focuses on molecular genetics and cancer biology. His work explores the mechanisms of chemoresistance in cancer, particularly involving the mTORC1 signaling pathway and its role in platinum-based chemotherapy resistance. He also investigates the epigenomic and transcriptomic changes related to chemoresistance in colorectal cancer cells. His expertise extends to drug discovery, with a focus on molecular dynamics and virtual screening for targeting cancer resistance mechanisms. Alizadeh’s research contributes significantly to understanding cancer cell survival and potential therapeutic strategies. 🧬💉💡

 

Publication Top Notes

  • Introduction of AGPAT3 gene as a regulator of cisplatin resistance in A2780 ovarian cancer
    cell line (under review after revision in PLOS ONE)
  •  Phosphatidic acid as a cofactor of mTORC1 in platinum-based chemoresistance: Mechanisms
    and therapeutic potential (Review article) (Published)
  •  Epigenomic and Transcriptomic Profiling of Oxaliplatin Resistant HCT116 Colorectal
    Cancer Cells Reveals Super-Enhancer-Driven Mechanisms of Chemoresistance
    (Bioinformatic article) (Revision in Scientific Reports)
  • Comparison of Machine Learning Algorithms and Feature Selection Methods for Identifying
    Important Features of Expression Data (Manuscript preparation)
  • Bioinformatic Analysis to find drugs Inhibiting mTORC1 as a Phosphatidic AcidDisplacement Strategy (Manuscript preparation)
  •  Comparison of Signaling Pathways and Genetic Modifications of Cancer Stem Cells with
    Normal Stem Cells (Review article) (ready to submit)

 

 

 

Lan Hong | Stem cell Therapy | Best Researcher Award

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Prof. Lan Hong | Stem cell Therapy | Best Researcher Award

Prof. Lan Hong, Department of Physiology and Pathophysiology College of Medicine, Yanbian University, China

Prof. Lan Hong is a distinguished professor and doctoral supervisor at Yanbian University, China, specializing in physiology and pathophysiology. With a Ph.D. in Physiology from Yanbian University, her research focuses on myocardial infarction, cardiac endocrine hormones, and stem cell therapy for heart regeneration. Prof. Hong has held prominent roles at Texas A&M University and led several significant research projects funded by the National Natural Science Foundation of China. She is an active member of various scientific societies, including the Chinese Physiological Society. Her research aims to uncover novel mechanisms for cardiovascular protection and regeneration. 🌟🫀

Publication Profile

Google Scholar

Education 🎓

Prof. Lan Hong completed his educational journey at Yanbian University School of Medicine, Yanji, China. He earned his Ph.D. in Physiology and Pathophysiology (2009-2012), following a Master’s degree in the same field (2006-2009). His foundational studies were rooted in Clinical Medicine, culminating in a Bachelor’s degree (2001-2006). Prof. Hong’s extensive academic background laid the groundwork for his pioneering research in cardiovascular health, particularly in myocardial infarction, cardiac regeneration, and stem cell therapies. His educational achievements reflect his deep commitment to advancing medical science and physiology. 📚💉

 

Professional Experience 💼

Prof. Lan Hong is currently a Professor at the Yanbian University School of Medicine (2024–Present) in the Department of Physiology and Pathophysiology. Previously, he served as an Associate Professor at the same institution (2019–2023). Prof. Hong has also made significant contributions to regenerative medicine during his time in the Biomedical Institute for Regenerative Research (BIRR) at Texas A&M University – Commerce, Texas, where he worked as a Research Assistant (2019), Research Assistant Professor (2017–2018), and Postdoctoral Research Associate (2017). His earlier academic role included an Instructor position at Yanbian University (2013–2017). 🌍🔬

 

Research Support 🔬💡

Prof. Lan Hong has led numerous groundbreaking research projects as a Principal Investigator. Currently, he is investigating how LncRNA-CIR can repair infarcted hearts by inducing MSCs into cardiomyocytes through CDK1, supported by the National Natural Science Foundation of China (2024–2027). His prior work includes exploring ANP’s cardioprotective effects against ischemia/reperfusion injury (2018–2021), as well as preclinical studies on induced pluripotent stem cell therapy for myocardial infarction (2021–2024). Prof. Hong has also led projects on Ginseng’s effects on myocardial protection and Schisandrin B‘s impact on ischemic injury, further advancing cardiovascular research. ❤️🧬

 

Research Focus Areas 🔬❤️

Prof. Lan Hong’s research spans multiple facets of cardiovascular physiology, cell signaling, and pharmacology. His work primarily investigates the secretion of atrial natriuretic peptide (ANP) in response to hypoxic conditions and various pharmacological agents. His studies explore pathways like MAPK, PI3K, and HIF-1α, which regulate cardiac function and response to injury. Additionally, Prof. Hong has contributed significantly to antimicrobial drug development, particularly against methicillin-resistant Staphylococcus aureus (MRSA) and other resistant pathogens. His research also delves into mitochondrial stress, cell signaling pathways, and pharmacological interventions for myocardial protection. 💉🧬⚡

 

Publication Top Notes

  • Synthesis and antibacterial evaluation of rhodanine-based 5-aryloxy pyrazoles against MRSA and QRSA – European Journal of Medicinal Chemistry, 2013 (57 citations) 🦠
  • MAPK and PI3K pathways regulate hypoxia-induced atrial natriuretic peptide secretion – Biochemical and Biophysical Research Communications, 2013 (38 citations) 💓
  • Atrial natriuretic peptide prevents mitochondrial permeability transition pore opening – European Journal of Pharmacology, 2012 (37 citations) 🔬
  • Synthesis and biological evaluation of 5-aryloxypyrazole derivatives as potential antimicrobial agents – Bioorganic & Medicinal Chemistry Letters, 2012 (35 citations) 💊
  • Synthesis and positive inotropic activity of quinolin-7-yl derivatives – Bioorganic & Medicinal Chemistry Letters, 2008 (26 citations) 💥
  • Adenosine A2 receptor activation ameliorates mitochondrial oxidative stress – Free Radical Biology and Medicine, 2017 (22 citations) ⚡
  • Ethanol attenuates sensory responses in cerebellar granule cells – Neuroscience Letters, 2014 (19 citations) 🍷
  • Ouabain stimulates atrial natriuretic peptide secretion via endothelin-1/ETB receptor – Life Sciences, 2012 (16 citations) 💧
  • Cathepsins in the extracellular space: Focusing on non-lysosomal proteolytic functions – Cellular Signaling, 2023 (13 citations) 🔬
  • Endogenous ET-1 promotes ANP secretion in hypoxic beating rat atria – Peptides, 2019 (12 citations) 🌱