İlhan Sabancılar | Molecular Oncology | Best Researcher Award

Assist. Prof. Dr. İlhan Sabancılar | Molecular Oncology | Best Researcher Award

Bitlis Eren University | Turkey

Assist. Prof. Dr. İlhan Sabancılar is a biochemist and medical researcher at Bitlis Eren University, Turkey, whose work bridges biochemistry, molecular medicine, and pharmaceutical sciences. His research primarily focuses on the anticancer, antioxidant, antimicrobial, and anti-inflammatory properties of bioactive compounds, natural extracts, and nanomaterials. Assist. Prof. Dr. İlhan Sabancılar has contributed to the synthesis and biological evaluation of novel heterocyclic and aza-acyclic nucleoside derivatives, investigating their potential as therapeutic agents through molecular docking and cytotoxicity studies. His publications in journals such as Pharmaceuticals, Current Issues in Molecular Biology, and Reviews on Environmental Health reflect his expertise in oxidative stress, trace element biochemistry, and drug development. With 9 publications and 247 citations, he has established a growing scientific presence supported by multiple research projects on oxidative stress, viral inhibition, and cancer therapeutics. A member of the Turkish Biochemical Society and the Molecular Cancer Research Association, Assist. Prof. Dr. İlhan Sabancılar’s multidisciplinary approach and consistent research output position him as a promising scholar contributing significantly to the advancement of biomedical and biochemical sciences.

Profile: Scopus | Orcid | Google Scholar

Featured Publications

1. Unsal, V., Cicek, M., & Sabancilar, İ. (2021). Toxicity of carbon tetrachloride, free radicals and role of antioxidants. Reviews on Environmental Health, 36(2), 279–295.

2. Bilden, A., Sabancılar, İ., Yalçın Azarkan, S., Karadağlı, K., Kaya, S., Kahraman, M., & Çiçek, M. (2025). Investigating the therapeutic potential of crude leech saliva based on its anticancer, antioxidant, and anti-inflammatory effects. Current Issues in Molecular Biology, 47(5), 328.

3. Sabancilar, İ., Unsal, V., Demir, F., Toprak, G., & Pekkolay, Z. (2023). Does oxidative status affect serum sclerostin levels in patients with type 2 diabetes mellitus? Folia Medica, 65(1), 46–52.

4. Alhilal, M., Alhilal, S., Gomha, S. M., Farag, B., Sabancilar, İ., & Ouf, S. A. (2025). Biological evaluation and molecular docking studies of novel aza-acyclic nucleosides as putative antimicrobial, anticancer, and antioxidant agents. BMC Chemistry, 19(1), 255.

5. Muhammed Ayral, H. T., Toprak, S. F., Dedeoğlu, S., & Sabancılar, İ. (2021). Kronik Otitis Media’da Tiyol-Disülfid Homeostazının Değişikliği. Dicle Tıp Dergisi, 48(1), 197–204.

6. Toprak, G., Sabancılar, İ., Özcan, N., & Alkan, H. (2020). Total oxidant status (TOS), total antioxidant status (TAS), ferritin and vitamin D levels in patients with chronic hepatitis C. Microbiology and Infectious Diseases, 4(2), 1–4.

 

Hadi Alizadeh | Cancer stem cells | Best Researcher Award

Mr. Hadi Alizadeh | Cancer stem cells | Best Researcher Award

Graduate Master Student, Tarbiat Modares University, Iran

Mr. Hadi Alizadeh is a Master’s graduate in Molecular Genetics from Tarbiat Modares University, Tehran, with a thesis on AGPAT3 gene and cisplatin resistance in ovarian cancer cells. His research encompasses gene expression analysis, drug discovery, and epigenomic profiling, focusing on chemoresistance mechanisms in cancer. He has contributed to various publications and presented at international conferences. Skilled in PCR, RNA-seq, flow cytometry, and bioinformatics, he is proficient in machine learning and molecular dynamics. Hadi has been recognized for his academic excellence, ranking highly in national exams. He also has hands-on experience in medical genetics and as a teaching assistant. 🧬💉🔬

 

Publication Profile

Orcid

Education

Mr. Hadi Alizadeh completed his Master’s in Molecular Genetics at Tarbiat Modares University, Tehran, from October 2021 to November 2023, achieving an impressive average of 18.2/20. His thesis, titled “Introduction of AGPAT3 gene as a regulator of cisplatin resistance in A2780 ovarian cancer cell line,” was supervised by Dr. Soltani. Prior to this, he earned a Bachelor’s degree in Genetics from Islamic Azad University, North Tehran, from October 2016 to May 2020, with a strong academic performance, securing an average of 17.83/20. His solid educational background highlights his commitment to molecular genetics and cancer research. 📚🧬

 

Research Experience

Mr. Hadi Alizadeh’s research experience includes significant work in molecular genetics and cancer research. For his Master’s thesis, he explored AGPAT3 gene as a regulator of cisplatin resistance in ovarian cancer cells, performing RNA-seq and various functional assays like RT-qPCR, western blotting, and apoptosis assays, revealing AGPAT3’s role in survival and cell cycle arrest under cisplatin treatment. He also studied the synergistic effect of dendrosomal nano-curcumin (DNC) with cisplatin in reducing cisplatin resistance. Additionally, he worked on epigenomic profiling of oxaliplatin-resistant HCT116 colorectal cancer cells and drug discovery targeting mTORC1 signaling. 🧬💻

 

Honors & Awards 🏆🎓

Mr. Hadi Alizadeh has demonstrated exceptional academic achievements throughout his career. In 2021, he ranked 18th out of nearly 10,000 participants in the national entrance exam for medical genetics in the healthcare system, showcasing his expertise and dedication. Additionally, he secured the 25th position among approximately 7,000 candidates in the national entrance exam for a Master’s program in genetics. These prestigious rankings highlight his strong academic foundation and passion for genetics research, setting the stage for his future contributions to the field. 🌟📚

 

Professional Experience 💼🔬

Mr. Hadi Alizadeh has gained valuable hands-on experience in various research and clinical settings. As a volunteer at Imam Khomeini Hospital in Tehran, he collected samples and performed RNA extraction for various projects. In his role as an apprentice at the Cytogenetic Lab, he conducted karyotyping as part of clinical genetic analyses, gaining key insights into genetic disorders. Additionally, as a Genetic Laboratory Technician prior to his Master’s, Mr. Alizadeh contributed to the COVID-19 response by performing RNA extraction and real-time PCR on samples, further honing his technical expertise in molecular genetics. 🧬🔬

 

Research Focus

Mr. Hadi Alizadeh’s research primarily focuses on molecular genetics and cancer biology. His work explores the mechanisms of chemoresistance in cancer, particularly involving the mTORC1 signaling pathway and its role in platinum-based chemotherapy resistance. He also investigates the epigenomic and transcriptomic changes related to chemoresistance in colorectal cancer cells. His expertise extends to drug discovery, with a focus on molecular dynamics and virtual screening for targeting cancer resistance mechanisms. Alizadeh’s research contributes significantly to understanding cancer cell survival and potential therapeutic strategies. 🧬💉💡

 

Publication Top Notes

  • Introduction of AGPAT3 gene as a regulator of cisplatin resistance in A2780 ovarian cancer
    cell line (under review after revision in PLOS ONE)
  •  Phosphatidic acid as a cofactor of mTORC1 in platinum-based chemoresistance: Mechanisms
    and therapeutic potential (Review article) (Published)
  •  Epigenomic and Transcriptomic Profiling of Oxaliplatin Resistant HCT116 Colorectal
    Cancer Cells Reveals Super-Enhancer-Driven Mechanisms of Chemoresistance
    (Bioinformatic article) (Revision in Scientific Reports)
  • Comparison of Machine Learning Algorithms and Feature Selection Methods for Identifying
    Important Features of Expression Data (Manuscript preparation)
  • Bioinformatic Analysis to find drugs Inhibiting mTORC1 as a Phosphatidic AcidDisplacement Strategy (Manuscript preparation)
  •  Comparison of Signaling Pathways and Genetic Modifications of Cancer Stem Cells with
    Normal Stem Cells (Review article) (ready to submit)

 

 

 

Hyunsook Lee | Cancer Cell Biology | Best Researcher Award

Prof Dr. Hyunsook Lee | Cancer Cell Biology | Best Researcher Award

Prof Dr. Hyunsook Lee, Seoul National University/College of Natural Sciences/Dept. of Biological Sciences, South Korea

🎓 Prof. Dr. Hyunsook Lee is an accomplished scientist with a diverse educational background: B.Sc. from Ewha Womans University, M.Sc. from Seoul National University, and a Ph.D. from the University of Cambridge under Prof. Ashok Venkitaraman. Her research focused on cell cycle checkpoints and the breast cancer susceptibility gene, Brca2. Dr. Lee holds key positions including Head of AI-Bio Research Center and Dean for Research Affairs at Seoul National University. She co-founded Next & Bio, later acquired by Kolmar Holdings, and has served on advisory boards for STEPI and the Ministry of Education in Korea. 🧬

 

Publication profile

Google Scholar

🎓 Education

Prof. Dr. Hyunsook Lee earned her B.Sc. from Ewha Womans University (1986-1990) and M.Sc. from Seoul National University (1990-1992). She completed her Ph.D. at the University of Cambridge (1996-1999), focusing on cell cycle checkpoints and the breast cancer gene, Brca2, under the supervision of Prof. Ashok Venkitaraman.

🌟 Professional Achievements

Dr. Lee holds numerous prestigious positions, including Head of AI-Bio Research Center (since 2023) and co-founder of Next & Bio (acquired by Kolmar Holdings in 2022). She served as Dean for Research Affairs at Seoul National University and on advisory committees for STEPI and the Ministry of Education in Korea.

Experience

Her career includes roles as a Visiting Scientist at Harvard Medical School and the University of Washington, and she contributed significantly to institutions like Samsung Advanced Institute of Technology.

 

Research Focus

Dr. H. Lee’s research spans across several fields, primarily focusing on technological advancements and their impacts. His work includes studies on augmented and virtual reality, high-frequency electrical models, and the application of IT in organizational contexts. With interests ranging from cultural heritage tourism to smart home services, Dr. Lee’s research integrates diverse disciplines to explore innovative solutions and their societal implications. 🌐

Publication Top Notes

📄 Nature 425 (6961), 968-973 – Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes (2152 citations, 2003)

📊 Public administration review 66 (3), 370-385 – The impact of organizational context and information technology on employee knowledge-sharing capabilities (1149 citations, 2006)

🔬 Molecular cell 1 (3), 347-357 – Involvement of Brca2 in DNA repair (789 citations, 1998)

🖥️ IEEE Journal of Solid-state circuits 19 (6), 820-827 – Full-speed testing of A/D converters (702 citations, 1984)

🏛️ Information and communication technologies in tourism 2016 – Effects of virtual reality and augmented reality on visitor experiences in museums (636 citations, 2016)

🧲 Physical Review B—Condensed Matter and Materials Physics 72 (17), 174431 – Magnetic ordering at the edges of graphitic fragments (563 citations, 2005)

🧠 Brain research 971 (2), 197-209 – Astrocytes accumulate Aβ42 and give rise to astrocytic amyloid plaques in Alzheimer disease brains (538 citations, 2003)

🔌 IEEE Transactions on Components, Packaging and Manufacturing Technology 1 (2) – High-frequency scalable electrical model and analysis of a through silicon via (TSV) (509 citations, 2011)

🏗️ Cement and Concrete research 32 (8), 1313-1318 – Evaluation of the bond properties between concrete and reinforcement as a function of the degree of reinforcement corrosion (496 citations, 2002)

🏛️ Journal of Travel Research 57 (5), 627-643 – The role of augmented reality for experience-influenced environments: The case of cultural heritage tourism in Korea (403 citations, 2018)

🏠 Industrial Management & Data Systems 117 (1), 68-89 – User acceptance of smart home services: an extension of the theory of planned behavior (395 citations, 2017)

🌿 Proceedings of the National Academy of Sciences 87 (19), 7633-7637 – Wound-induced accumulation of mRNA containing a hevein sequence in laticifers of rubber tree (362 citations,