Dr. Angélique Nicolas Messi | Organic Chemistry | Best Researcher Award
University of Yaoundé 1 | Cameroon
Dr. Angélique Nicolas Messi is a researcher specializing in pharmaceutical and natural products chemistry, with a focus on discovering bioactive compounds from medicinal plants. Her work emphasizes neuroprotection, anticancer, antimalarial, anti-HIV/AIDS, and anti-neuroinflammatory activities, targeting both natural and synthetic compounds. She employs bioguided isolation, synthesis of flavonoids and biflavonoids, and advanced spectroscopic techniques (1D and 2D NMR) for drug discovery and chemotaxonomy. Dr. Angélique Nicolas Messi has published 11 papers, cited over 70 times, with an h-index of 4, covering topics such as antileishmanial agents from Tarenna conferta, HIV-1 inhibitors from Ochna rhizomatosa, and plant-derived alkaloids for leukemia and malaria drug development, highlighting her contribution to understanding the pharmacological potential of African flora.
Profile: Scopus | Google Scholar
Featured Publications
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Ndongo, J. T., Issa, M. E., Messi, A. N., Ngo Mbing, J., Cuendet, M., & Pegnyemb, D. E., et al. (2015). Cytotoxic flavonoids and other constituents from the stem bark of Ochna schweinfurthiana. Natural Product Research, 29(17), 1684–1687.
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Messi, A. N., Mbing, J. N., Ndongo, J. T., Nyegue, M. A., Tchinda, A. T., & Yemeda, F. L., et al. (2016). Phenolic compounds from the roots of Ochna schweinfurthiana and their antioxidant and antiplasmodial activities. Phytochemistry Letters, 17, 119–125.
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Djova, S. V., Nyegue, M. A., Messi, A. N., Afagnigni, A. D., & Etoa, F. X. (2019). Phytochemical study of aqueous extract of Ochna schweinfurthiana F. Hoffm powder bark and evaluation of their anti-inflammatory, cytotoxic, and genotoxic activities. Evidence-Based Complementary and Alternative Medicine, 2019, 8908343.
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Messi, A. N., Bonnet, S. L., Owona, B. A., Wilhelm, A., Kamto, E. L. D., & Ndongo, J. T., et al. (2022). In vitro and in silico potential inhibitory effects of new biflavonoids from Ochna rhizomatosa on HIV-1 integrase and Plasmodium falciparum. Pharmaceutics, 14(8), 1701.
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Nyegue, M. A., Mbing, J. N., Djova, S. V., Messi, A. N., Olugu, S. V., & Pegnyemb, D. E., et al. (2016). Evaluation of the antioxidant activity of the leaves, stem-barks extracts and fractions of Ochna schweinfurthiana F. Hoffm (Ochnaceae). African Journal of Pharmacy and Pharmacology, 10(17), 370–378.