Mohammad-Mehdi Khani | Tissue Engineering | Best Researcher Award

Assoc. Prof. Dr. Mohammad-Mehdi Khani | Tissue Engineering | Best Researcher Award

Shahid Beheshti University of Medical Sciences | Iran

Assoc. Prof. Dr. Mohammad-Mehdi Khani, Associate Professor at the Department of Tissue Engineering and Applied Cell Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran, demonstrates exceptional expertise in biomechanics, tissue engineering, and regenerative medicine. With a Ph.D. in Biomedical Engineering (Biomechanics) from Amir-Kabir University of Technology, he has produced 61 publications with 767 citations and an h-index of 16, reflecting his significant scholarly impact. His research spans cell mechanics, mechanobiology, stem cell engineering, functional tissue engineering, cardiovascular and corneal regeneration, and regenerative medicine, bridging fundamental science with translational applications. Assoc. Prof. Dr. Mohammad-Mehdi Khani’s notable achievements include membership in Iran’s National Elites Foundation, recognition as a talented graduate, and the Nightingale Award for the best paper in Medical and Biological Engineering and Computing (2021). His work encompasses advanced studies on hydrogel-derived matrices, nanofibrous cardiac patches, stem cell differentiation, bioreactor cultivation, and computational modeling, significantly contributing to the understanding and development of innovative therapeutic strategies in tissue repair and biomedical engineering.

Profile: Scopus| Orcid | Google Scholar

Featured Publications

Moradi, S. L., Golchin, A., Hajishafieeha, Z., Khani, M. M., & Ardeshirylajimi, A. (2018). Bone tissue engineering: Adult stem cells in combination with electrospun nanofibrous scaffolds. Journal of Cellular Physiology, 233(10), 6509–6522.

Abazari, M. F., Soleimanifar, F., Amini Faskhodi, M., Mansour, R. N., & Khani, M. M. (2020). Improved osteogenic differentiation of human induced pluripotent stem cells cultured on polyvinylidene fluoride/collagen/platelet‐rich plasma composite nanofibers. Journal of Cellular Physiology, 235(2), 1155–1164.

Abazari, M. F., Soleimanifar, F., Enderami, S. E., Nematzadeh, M., Nasiri, N., & Khani, M. M. (2019). Incorporated-bFGF polycaprolactone/polyvinylidene fluoride nanocomposite scaffold promotes human induced pluripotent stem cells osteogenic differentiation. Journal of Cellular Biochemistry, 120(10), 16750–16759.

Jouybar, A., Seyedjafari, E., Ardeshirylajimi, A., Zandi-Karimi, A., & Feizi, N. (2017). Enhanced skin regeneration by herbal extract-coated poly-L-lactic acid nanofibrous scaffold. Artificial Organs, 41(11), E296–E307.

Saffar, R. J., Razfar, M. R., Salimi, A. H., & Khani, M. M. (2009). Optimization of machining parameters to minimize tool deflection in the end milling operation using genetic algorithm. World Applied Sciences Journal, 6(1), 64–69.

Yanlian Chen | Senescence | Best Researcher Award

Assoc. Prof. Dr. Yanlian Chen | Senescence | Best Researcher Award

Assoc. Prof. Dr. Yanlian Chen, Sun Yat-sen University, China

Dr. Yanlian Chen is an Associate Professor at The Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen, China. She earned her Ph.D. in Cell Biology and B.Sc. in Biotechnology from Sun Yat-sen University. Dr. Chen’s research advances understanding of vascular calcification, cancer immunotherapy, telomere biology, and viral infection control. She has led multiple national and provincial research projects and holds several patents. Her work is widely published in prestigious journals like Cancer Immunology Research and Signal Transduction and Targeted Therapy. She is an active member of leading medical associations, contributing significantly to vascular and hypertension research. 🌟

Publication Profile

Scopus

Education 📚

Yanlian Chen completed her Bachelor of Science in Biotechnology (2009-2013) and Ph.D. in Cell Biology (2013-2018) at the School of Life Sciences, Sun Yat-sen University, China. During her academic training, she gained extensive expertise in molecular biology, cellular signaling pathways, and translational medicine. Her doctoral research provided deep insights into telomere maintenance and RNA-binding proteins, laying a strong foundation for her future work on vascular calcification and immune modulation. Her comprehensive education enabled her to develop a multidisciplinary approach, bridging molecular mechanisms with clinical applications in vascular disease and cancer biology. 🎓

Experience 🧪

Dr. Chen began her academic career as a Postdoctoral Fellow at Sun Yat-sen University (2018-2021), where she studied tumor DNA damage tolerance. She then progressed to Assistant Researcher (2021-2024) and now serves as Associate Researcher (2024–present) at The Eighth Affiliated Hospital of Sun Yat-sen University. Throughout her career, she has spearheaded numerous high-impact research projects, managed interdisciplinary collaborations, and contributed to innovations in vascular health and cancer immunotherapy. Her clinical translational focus blends fundamental cell biology with therapeutic intervention strategies, leading to both significant publications and multiple patents. 🔬

Awards and Honors 🏆

Dr. Chen has been recognized for her excellence in research with prestigious awards, including the Third Prize of the Chinese Medical Science and Technology Award by the Chinese Medical Association in 2023 and the First Prize from the Guangdong Medical Association the same year. These honors reflect her pioneering work in understanding and intervening in hypertension-induced vascular injury. Additionally, she holds important professional roles, such as Standing Committee Member positions in the Pan-Vascular Disease Professional Committee and the Hypertension Branch of Guangdong Precision Medicine Application Society. Her accolades highlight her leadership and innovation in biomedical research. 🥇

Research Focus 🔬

Dr. Chen’s research focuses on the molecular mechanisms regulating vascular calcification, cancer immunotherapy targeting PD-L1 pathways, telomere stability, and anti-viral strategies against SARS-CoV-2. Her work integrates cellular biology with translational medicine, particularly investigating the roles of SIRT1 ubiquitination, MOV10/TERRA axis, and Let-7 microRNA pathways. She also explores therapeutic interventions for vascular aging and damage through metabolic modulation and immune checkpoint inhibitors. Her studies are aimed at developing novel clinical treatments for cardiovascular diseases and cancer, bridging laboratory discoveries with real-world health applications. Her research is cutting-edge and highly impactful. ⚡

Publication Top Notes

The transcription factor GATA6 accelerates vascular smooth muscle cell senescence-related arterial calcification by counteracting the role of anti-aging factor SIRT6 and impeding DNA damage repair

 

Shouhong Wang | Regeneration | Best Researcher Award

Assoc. Prof. Dr. Shouhong Wang | Regeneration | Best Researcher Award

Assoc. Prof. Dr. Shouhong Wang, chengdu institute of biology, China

Assoc. Prof. Dr. Shouhong Wang is a researcher focused on organ/tissue regeneration, with expertise in the use of frog models (Xenopus) to study thyroid hormone (T3) signaling in developmental and regenerative processes. He earned a PhD in Zoology from the Chengdu Institute of Biology and completed a postdoc at the NICHD, NIH. His research aims to advance human regeneration and improve quality of life through understanding organ regeneration. Dr. Wang has published extensively and presented at numerous international conferences. He is a member of the American Thyroid Association, Chinese Society for Cell Biology, and more. 🐸🔬📚

 

 

Publication Profile

Scopus

Academic Qualifications

Assoc. Prof. Dr. Shouhong Wang’s academic journey includes a Postdoctoral Fellowship in Molecular Morphogenesis at NICHD, National Institutes of Health (2019), where he studied the role of thyroid hormone (T3) signaling in tail regeneration under the supervision of Yun-Bo Shi. He earned his PhD in Developmental Biology from Chengdu Institute of Biology, Chinese Academy of Sciences (2016-2018), researching embryo development and gene regulation in Microhyla fissipes. Dr. Wang also holds an MSc in Zoology (2013-2015) from the same institute, focusing on frog tail development and apoptosis. He completed his BSc in Animal Sciences at Sichuan Agricultural University (2009-2013).

Awards & Grants

Assoc. Prof. Dr. Shouhong Wang has been recognized for his academic excellence throughout his career. He received a scholarship three times during his studies at Sichuan Agricultural University (2009-2013) and was honored as an Outstanding Graduate in 2013. In 2015, he earned the Outstanding Student Academic Oral Report award from the Chinese Herpetological Society and was named a Merit Student by the Chinese Academy of Sciences (2015-2016). Additionally, Dr. Wang received the Excellence Award in Science Popularization from the Chinese Society for Cell Biology in 2015-2016, acknowledging his contributions to scientific communication.

 

 

Teaching Experience

Assoc. Prof. Dr. Shouhong Wang has a strong background in teaching and mentoring. He has tutored high school students, helping them develop a deeper understanding of biology and related subjects. Additionally, Dr. Wang has shared his expertise at various training organizations and welfare centers for children, contributing to their educational development. His dedication to teaching extends beyond the classroom, as he strives to inspire young minds and foster a passion for science, ensuring the next generation is equipped with the knowledge and skills to thrive.

 

 

Research Focus

Assoc. Prof. Dr. Shouhong Wang’s research is centered on the mechanisms of organ and tissue regeneration, with the aim of improving human regeneration processes and quality of life. By utilizing model animals, particularly the frog system, Xenopus, Dr. Wang explores the role of thyroid hormone (T3) signaling in developmental regulation of organ regeneration. His work is focused on understanding how thyroid hormone influences regeneration and utilizing knockout animals to investigate its effects. Ultimately, this research could contribute to advancements in repairing and replacing damaged human organs and tissues.

 

 

Publication Top Notes

  • “Dose-dependent toxic effects of triclosan on Rana omeimontis larvae: Insights into potential implications for neurodegenerative diseases” (Chen et al., 2025) 🧪
  • “Thyroid hormone receptor- and stage-dependent transcriptome changes affect the initial period of Xenopus tropicalis tail regeneration” (Wang et al., 2024) 🧬
  • “Protein arginine methyltransferase 1 regulates mouse enteroendocrine cell development and homeostasis” (Peng et al., 2024) 🧫
  • “Simplifying Genotyping of Mutants from Genome Editing with a Parallel qPCR-Based iGenotype Index” (Fu et al., 2024) 🔬
  • “Thyroid hormone receptor knockout prevents the loss of Xenopus tail regeneration capacity at metamorphic climax” (Wang et al., 2023) 🦎
  • “Liver development during Xenopus tropicalis metamorphosis is controlled by T3-activation of WNT signaling” (Tanizaki et al., 2023) 🐸
  • “Comparative Analysis of Transcriptome Profiles Reveals Distinct and Organ-Dependent Genomic and Nongenomic Actions of Thyroid Hormone in Xenopus tropicalis Tadpoles” (Wang et al., 2023) 🌱
  • “Essential and subtype-dependent function of thyroid hormone receptors during Xenopus metamorphosis” (Shi et al., 2023) 📚
  • “Osteological development of a small and fast metamorphic frog, Microhyla fissipes” (Zhang et al., 2021) 🦴