Prof. Huapan Fang, Xiamen University, China
Prof. Huapan Fang is an Associate Professor and Doctoral Supervisor at the College of Chemistry and Chemical Engineering, Xiamen University. He specializes in polymer chemistry, nanomedicine, and biomedical materials. With a Ph.D. from the University of Science and Technology of China, he has held research roles at the Chinese Academy of Sciences, Suzhou University, and Xiamen University. Prof. Fang has published extensively in Nature Communications, ACS Nano, JACS, and more, contributing significantly to gene delivery, immunotherapy, and biomaterials. He is recognized for his innovative research and is a recipient of multiple high-level talent honors. ๐งช๐๐จ๐ณ
Publication Profile
Scopus
๐ Education
Prof. Fang earned his Ph.D. in Polymer Chemistry and Physics from the University of Science and Technology of China (2014โ2019), where he conducted pioneering research in gene transfection materials and polymeric drug delivery. Prior to that, he completed his Bachelorโs degree in Polymer Materials and Engineering at Hubei University (2010โ2014), building a strong foundation in synthetic and applied polymer science. His academic journey reflects a continuous trajectory in high-level interdisciplinary training, blending polymer chemistry with biomedical applications. This rigorous education positioned him at the forefront of next-generation polymeric biomaterials and nanotherapeutics. ๐๐๐ฌ
๐ผ Experience
Since January 2023, Prof. Fang has been serving as Associate Professor and Doctoral Supervisor at Xiamen University, also holding the title of Nanqiang Young Top Talent. From 2020 to 2022, he was a postdoctoral researcher at the Institute of Functional Nano & Soft Materials, Soochow University. Before that, he worked at the Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, as an Assistant Researcher from late 2019 to mid-2020. His professional experience spans leading Chinese institutions and research labs, focusing on cutting-edge topics in nanomedicine, polymers, and biomaterial-based drug delivery. ๐งโ๐ฌ๐ซ๐งซ
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Awards & Honors
Prof. Huapan Fang has been honored with the Chinese Academy of Sciences Presidentโs Excellence Award in 2019, recognizing his outstanding Ph.D. research contributions. He was named a High-Level Talent in Fujian Province (2023) and in Xiamen City (2024), highlighting his scientific leadership and innovation. As a Nanqiang Young Top Talent at Xiamen University, he is acknowledged as a rising figure in polymer and nanomedical research. These accolades underscore his influential contributions to biomedical polymer science and the application of smart materials in cancer therapy and drug delivery. ๐๐๐จ๐ณ
๐ฌ Research Focus
Prof. Fangโs research centers on biomedical polymers, nanomedicine, and gene delivery systems. His work involves developing innovative polymeric materials for disease treatment, including cancer immunotherapy, mRNA vaccines, and pulmonary disease therapeutics. He explores the tumor microenvironment, polymer degradation, epigenetic regulation, and synergistic drug delivery approaches. His team combines polymer chemistry with biology to design responsive, targeted, and low-toxicity nanocarriers for effective clinical translation. His most cited works demonstrate breakthroughs in oral drug delivery, intraperitoneal chemotherapy, and inhalable siRNA nanoplatforms for fibrosis and cancer. ๐งฌ๐ฉบ๐งซ๐
Publication Top Notes
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๐งฌ Combination of epigenetic regulation with gene therapy-mediated immune checkpoint blockade induces anti-tumour effects and immune response in vivo, Nat. Commun., 2021, cited by many in cancer immunotherapy research. ๐งซ๐ก๏ธ
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๐งช Molecular strings significantly improved the gene transfection efficiency of polycations, J. Am. Chem. Soc., 2018, widely cited in gene delivery systems. ๐งฌ๐
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๐ In situ polymerization of zwitterions on therapeutic proteins to enable their effective oral delivery, ACS Nano, 2023, enhancing protein drug delivery research. ๐๐งช
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๐งซ Regulating the obesity-related tumor microenvironment to improve cancer immunotherapy, ACS Nano, 2023, linking obesity & tumor immunology. ๐๐งฌ
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๐งฌ Cancer cell membrane-enveloped dexamethasone normalizes the tumor microenvironment and enhances gynecologic cancer chemotherapy, ACS Nano, 2023, key in tumor microenvironment modulation. ๐งซ๐
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๐ฌ๏ธ Inhalable siRNA targeting IL-11 nanoparticles significantly inhibit bleomycin-induced pulmonary fibrosis, ACS Nano, 2025, novel for pulmonary fibrosis. ๐ซ๐งฌ
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๐ mRNA vaccines contribute to innate and adaptive immunity to enhance immune response In Vivo, Biomaterials, 2024, supports next-gen vaccine research. ๐๐ฆ
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๐ฅ Carrier-free multifunctional nanomedicine for enhanced hyperthermic intraperitoneal chemotherapy, Chem. Eng. J., 2024, revolutionizing HIPEC therapy. ๐ก๏ธ๐ฅ
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๐งช Latest advancements and trends in biomedical polymers for disease prevention, diagnosis, treatment, J. Controlled Release, 2025, comprehensive review in biomaterials. ๐งฌ๐
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๐ง Metabolism of cancer cells and immune cells in cancer initiation, progression, and metastasis, Theranostics, 2025, cited for cancer metabolism insights. โ๏ธ๐งฌ