Prof. Luis Sobrevia, Pontificia Universidad Católica de Chile, Chile
Prof. Luis Sobrevia is a distinguished Chilean physiologist with extensive academic and research credentials. He completed his BSc in Biological Sciences from Universidad del Bío-Bío, MSc in Physiological Sciences from Universidad de Concepción, and PhD in Physiology and Biomedicine from King’s College London. He has held postdoctoral training at King’s College London and earned a Diploma in University Teaching from Pontificia Universidad Católica de Chile (PUC). As a Fellow of The Physiological Society (UK) and the International Union of Physiological Sciences, he holds prominent academic positions worldwide, including at PUC, TecSalud in Mexico, and UNESP in Brazil. His research focuses on placental vascular dysfunction in pregnancy complications like gestational diabetes and obesity, studying pathways that affect maternal-fetal health. He has mentored numerous PhD and MSc students and collaborates globally on groundbreaking research. 🌍🔬
Education
Prof. Luis Sobrevia holds a BSc Hons. in Biological Sciences (1986) from Universidad del Bío-Bío, Chile, and an MSc in Physiology (1990) from Universidad de Concepción, Chile. He earned his PhD in Physiology and Biomedicine (1996) at King’s College London, UK, followed by a postdoctoral fellowship there. Prof. Sobrevia has held academic positions globally, currently serving as a Distinguished Research Professor at Tecnológico de Monterrey, Mexico, and as an Honorary Professor in Australia, Spain, and Brazil. His extensive experience spans physiology, biomedicine, and university teaching, making significant contributions to obstetrics and biomedical sciences. 🏥📚
Research
Prof. Luis Sobrevia leads an extensive research group comprising PhD students from various global institutions, such as PUC Chile, U Talca, UNESP Brazil, and U Coimbra, Portugal. His team includes MSc and undergraduate students, along with technical research assistants like biochemist K Silva. The group hosts postdoctoral researchers, including A Grismaldo and MA Pascon. Collaborations span prestigious institutions like University Medical Centre Groningen, TecSalud, and Karolinska Institutet. As a thesis supervisor, Prof. Sobrevia has mentored 69 students across PhD, MSc, and undergraduate levels, focusing on physiology, biomedicine, and molecular biology. 🌍📚💡
Teaching Experience 🎓📚
Prof. Luis Sobrevia is a dedicated educator, teaching undergraduate courses in Medicine, Biology, Biochemistry, Nutrition, and Bioethics. He also mentors postgraduate students, including PhD, MSc, and medical specialization programs. His teaching spans top universities in Chile (PUC, UCH, UT, UA, UACH, UDEC) and internationally at institutions like UMCG (Netherlands), US (Spain), KCL (UK), AUT (New Zealand), UQCCR (Australia), UNESP (Brazil), and TecMonterrey (Mexico). His expertise covers topics such as gestational diabetes, fetal vascular dysfunction, cardiovascular pathophysiology, endothelial physiology, and insulin and adenosine signaling. 🌍🩺📖
Academic and Scientific Merit Recognitions 🌟🏅
Prof. Luis Sobrevia has earned numerous prestigious awards and appointments throughout his academic career. In 2024, he was nominated as a Corresponding Member of the Chilean Academy of Sciences and recognized for his contributions to internationalization by the Mexican Society of Physiological Sciences. He was also appointed Co-president of the Regional Focal Point for Latin America and the Caribbean (RFP-LAC) of the International Science Council (ISC) and Editor-in-Chief of Physiological Minireviews. His leadership extends to roles such as Regional Editor for The Journal of Physiology and member of international scientific committees, highlighting his significant global impact. 🌍📚💡
Publication Top Notes
- Regulation of amino acid and glucose transporters in endothelial and smooth muscle cells by GE Mann, DL Yudilevich, L Sobrevia, Physiological reviews 83 (1), 183-252, Cited by: 578, 2003 📚💉
- A gestational profile of placental exosomes in maternal plasma and their effects on endothelial cell migration by C Salomon, MJ Torres, M Kobayashi, K Scholz-Romero, L Sobrevia, PloS one 9 (6), e98667, Cited by: 412, 2014 🤰🔬
- Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis by C Salomon, J Ryan, L Sobrevia, M Kobayashi, K Ashman, M Mitchell, PloS one 8 (7), e68451, Cited by: 400, 2013 🌱💧
- Oxidative stress: Normal pregnancy versus preeclampsia by DI Chiarello, C Abad, D Rojas, F Toledo, CM Vázquez, A Mate, Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1866 (2), 165354, Cited by: 325, 2020 🩸💔
- Hypoxia-induced changes in the bioactivity of cytotrophoblast-derived exosomes by C Salomon, M Kobayashi, K Ashman, L Sobrevia, MD Mitchell, GE Rice, PloS one 8 (11), e79636, Cited by: 213, 2013 🌍💫
- Dysfunction of the endothelial nitric oxide signalling pathway in diabetes and hyperglycaemia by L Sobrevia, GE Mann, Experimental Physiology: Translation and Integration 82 (3), 423-452, Cited by: 208, 1997 🧬🩺
- Activation of L‐arginine transport (system y+) and nitric oxide synthase by elevated glucose and insulin in human endothelial cells by L Sobrevia, A Nadal, DL Yudilevich, GE Mann, The Journal of physiology 490 (3), 775-781, Cited by: 204, 1996 ⚡💡
- Mice long-term high-fat diet feeding recapitulates human cardiovascular alterations: an animal model to study the early phases of diabetic cardiomyopathy by SD Calligaris, M Lecanda, F Solis, M Ezquer, J Gutierrez, E Brandan, PloS one 8 (4), e60931, Cited by: 189, 2013 🍔❤️
- Extracellular vesicles in obesity and diabetes mellitus by F Pardo, R Villalobos-Labra, B Sobrevia, F Toledo, L Sobrevia, Molecular aspects of medicine 60, 81-91, Cited by: 187, 2018 🧬🍩
- Early activation of the p42/p44MAPK pathway mediates adenosine‐induced nitric oxide production in human endothelial cells: a novel calcium‐insensitive … by AW Wyatt, JR Steinert, CPD Wheeler‐Jones, AJ Morgan, D Sugden, The FASEB journal 16 (12), 1584-1594, Cited by: 155, 2002 🔬💡