Hu Zhou | Hematology | Excellence in Research Award

Prof. Dr. Hu Zhou | Hematology | Excellence in Research Award

Henan Cancer Hospital | China

Prof. Dr. Hu Zhou is a leading hematology researcher recognized for his extensive work on the pathogenesis and clinical management of blood disorders, particularly immune thrombocytopenia, myelodysplastic syndromes, myeloproliferative neoplasms, and thrombosis–hemostasis abnormalities. With 621 citations, 78 published documents, and an h-index of 14, he has established a strong scholarly footprint in clinical and translational hematology. His research integrates clinical trials, molecular pathology, and mechanistic studies, contributing significantly to advances in immunoglobulin therapies, monoclonal antibodies, JAK2 inhibitors, and recombinant thrombopoietic agents. He has illuminated genetic polymorphisms, cytokine signaling pathways, and immune dysregulation mechanisms underlying chronic immune thrombocytopenia. His contributions further extend to leukemogenesis, epigenetic alterations in hematologic malignancies, and therapeutic optimization in refractory leukemia. As an active member of national and international hematology societies, he leads major funded research projects and has been recognized with multiple scientific achievement awards, reflecting his broad impact on hematologic innovation and patient-centered clinical advancement.

Profile: Scopus

Featured Publications

1. Zhou, H., et al. (2025). Efficacy and safety of a new 10% intravenous immunoglobulin (IVIG) in Chinese patients with primary immune thrombocytopenia (ITP): A multicenter, single-arm, phase III trial. Clinical and Experimental Medicine.

2. Zhou, H., et al. (2025). Anti-CD38 monoclonal antibody CM313 for primary immune thrombocytopenia: Multicentre, randomised, placebo-controlled, phase 2 trial. BMJ Clinical Research Edition.

3. Zhou, H., et al. (2025). Efficacy and safety of OB756 (a novel selective JAK2 inhibitor) for essential thrombocythemia in patients intolerant of or resistant to hydroxyurea or intolerant of interferon: A phase 2, open-label, multicenter study. Cancer.

4. Zhou, H., et al. (2025). Hetrombopag for patients with persistent primary immune thrombocytopenia: A post hoc analysis of a multicenter, randomized phase III trial. Research and Practice in Thrombosis and Haemostasis.

5. Zhou, H., et al. (2025). Dose-optimised recombinant human thrombopoietin versus eltrombopag in patients with immune thrombocytopenia: A multicenter, randomised controlled trial (The TE-ITP Study). EClinicalMedicine.

Betty Pace | Hematology | Best Researcher Award

Dr. Betty Pace | Hematology | Best Researcher Award

Dr. Betty Pace, Augusta University, United States

Dr. Betty Sue Pace, MD, is a Professor with tenure at Augusta University, serving in the Departments of Pediatrics and Biochemistry & Molecular Biology. 🧬 She holds the prestigious Francis J. Tedesco Distinguished Chair in Pediatric Hematology/Oncology and is a member of the Georgia Cancer Center. 🌟 With a medical degree from the Medical College of Wisconsin and postdoctoral training at the University of Washington, Dr. Pace is a leader in sickle cell disease research. ❤️ She has directed major research centers and served on national committees, including NIH and ASH. 📚 Her work promotes diversity, inclusion, and scientific advancement.

Publication Profile

Scopus

🎓 Education & Training

Dr. Betty Sue Pace began her academic journey at Lake Forest College in 1973, later earning her B.S. in Mathematics from Marquette University in 1976. ➗ She pursued her M.D. in Medicine at the Medical College of Wisconsin, graduating in 1981. 🩺 Dr. Pace completed her Pediatric Internship and Residency (1981–1984) at the same institution’s Children’s Hospital. 👶 She further specialized through a Pediatric Hematology/Oncology Fellowship at the University of Colorado Health Sciences Center (1987–1990). 🧬 In 1990, she briefly served as a Locum Tenens Pediatrician before undertaking a Postdoctoral Research Fellowship at the University of Washington (1990–1994).

🏅 Awards & Honors

Dr. Betty Sue Pace has received numerous prestigious accolades throughout her career. 🌟 In 1981, she was honored with the Kaiser Foundation Merit Award, Mosby Mirror Award, and Alpha Omega Alpha induction. 🏆 A Harold Amos Scholar in 1990, she was later named among Popular Science’s “Brilliant 10” in 2003. 🧪 Her work earned her Lifetime Achievement (2007), Diversity Champion (2010), and Distinguished Researcher (2022) awards. 💼 She also established endowed scholarships in her name and currently serves as Editor-in-Chief of the Journal of Sickle Cell Disease (2025). 📰 Her honors reflect a legacy of excellence in science, service, and inclusion.

Research Focus

Dr. Betty S. Pace’s research is primarily centered on sickle cell disease (SCD), with a strong focus on oxidative stress, fetal hemoglobin induction, and gene regulation. 🧬 Her work explores epigenetic therapies, histone deacetylase inhibitors, and NRF2 activation to mitigate disease symptoms. 🧫 She utilizes transgenic models, CRISPR techniques, and microRNA therapies to induce fetal hemoglobin expression and reduce ferroptosis. 💉 Her interdisciplinary research bridges molecular biology, hematology, and genomic innovation, aiming to develop novel therapeutic strategies for SCD. 🧠 Through collaborative studies and translational science, she is advancing curative solutions and improving patient outcomes worldwide.

Publication Top Notes

📄 “Transsulfuration pathway activation attenuates oxidative stress and ferroptosis…”Communications Biology, 2025 | Cited by: 1 📚🧬

📄 “CT-101 flips the switch to fetal hemoglobin expression…”PLOS One, 2025 🧪🧬

📄 “Innovations in Drug Discovery for SCD Targeting Oxidative Stress and NRF2…”Review, 2025  💊🧠

📄 “Endothelial ENaC-a Restrains Oxidative Stress in Lung Capillaries…”Am J Respir Cell Mol Biol, 2025 | Cited by: 2 🫁🔬

📄 “Hematopoietic cell transplant vs standard care in adolescents…”Blood Advances, 2025  🧫🧒

📄 “miR-29b induces fetal haemoglobin via promoter demethylation…”Br J Haematol, 2025 🧬🧠

📄 “Correction to: CRISPR-mediated fetal chromatin domain ablations”Scientific Reports, 2022  🧪📘

📄 “Telehealth Use Among People with SCD During COVID-19…”Telemedicine & e-Health, 2024 | Cited by: 1 💻📞

📄 “Simvastatin-Mediated Nrf2 Activation in SCD Mice…”Antioxidants, 2024 | Cited by: 2 🧬🛡️

📄 “Emergency Department Visits by Individuals With SCD (1999–2020)…”Ajpm Focus, 2024 | Cited by: 6 🏥📈

 

Roselene Mesquita Augusto Passos | Hematology | Best Researcher Award

Dr. Roselene Mesquita Augusto Passos | Hematology | Best Researcher Award

Dr. Roselene Mesquita Augusto Passos, Universidade de São Paulo, Brazil

Dr. Roselene Mesquita Augusto Passos is a physician specializing in Pediatrics, Pediatric Hematology, and Bone Marrow Transplantation. She graduated in Medicine from UNISA (1993), completed her medical residency at USP, and completed additional training in oncohematology in the USA. She is currently the technical manager of the BMT service at Hospital Brigadeiro, a physician at Hospital 9 de Julho and Hospital Alemão Oswaldo Cruz, and a PhD student at FMUSP, studying the cost-effectiveness of plerixafor. She also works at the Cancer Center in São Paulo. She is the author of relevant publications in the area, focusing on BMT complications, pediatric sedation, and hematologic diseases.

Publication Profile

Orcid

Academic Background

Dr. Roselene Passos is a dedicated physician specializing in pediatric hematology. She earned her medical degree from the University of Santo Amaro (UNISA) in 1993 🎓 and completed a medical residency in pediatrics at the University of São Paulo (USP) between 1994 and 1996 🏥. She further specialized in pediatric hematology (1996–1998) under Dr. Vicente Odoni Filho and later trained in oncohematology at DeVos Children Hospital in the U.S. in 2005 🇺🇸. Currently, she is pursuing a PhD at HCFMUSP, focusing on the cost-effectiveness of plerixafor in stem cell mobilization for autologous transplantation 💉📊.

Professional Performance

Since 1997, Dr. Roselene Passos has served as a dedicated public servant with exclusive dedication, currently acting as the Technical Manager of the Bone Marrow Transplant (BMT) Unit at Brigadeiro Hospital ⚕️. She worked in the pediatric hematology unit from 1997 to 2009 and has been a physician in the hospital’s BMT Unit since June 2007 🧫. In April 2016, she assumed the role of Technical Manager of the BMT unit. Additionally, since 2020, she has been affiliated as a registered physician with an 8-hour weekly commitment in the same unit, contributing her expertise to hematologic care and transplantation 🌟.

Areas of activity

Dr. Roselene Passos specializes in key areas of Health Sciences, with a strong focus on pediatric hematology and bone marrow transplantation. Her primary field is Medicine, specifically within the subarea of Pediatric Hematology, where she provides expert care to children with blood disorders 👩‍⚕️🧒. She also holds specialization in Hematology, contributing to the diagnosis and treatment of complex hematologic conditions 🧪. Additionally, Dr. Passos is deeply engaged in the field of Bone Marrow Transplantation, playing a vital role in stem cell mobilization and transplant procedures for pediatric patients in need of advanced therapeutic care 🌱🧫

Awards and Professional Titles 🏅🩺📜

Dr. Roselene Mesquita Augusto Passos has earned notable professional titles that underscore her expertise in pediatric and hematologic care. In 2010, she was awarded the Specialist Title in Hematology and Hemotherapy by the Brazilian Association of Hematology and Hemotherapy, recognizing her advanced knowledge and contributions in blood disorders and treatment 💉🩸. Earlier, in 1996, she received the Specialist Title in Pediatrics from the Brazilian Society of Pediatrics, affirming her commitment to pediatric healthcare and child well-being 👶🩺. These distinctions highlight her dedication and excellence across both pediatric and hematologic disciplines. 🌟

Research Focus

Dr. Roselene Mesquita Augusto Passos specializes in hematology with a focus on the economic and clinical aspects of hematopoietic stem cell mobilization and leukapheresis for autologous transplantation. Her research primarily addresses the cost-effectiveness of using plerixafor in patients with multiple myeloma and lymphoma, particularly in comparison to preemptive versus rescue strategies. She is also involved in evaluating pharmacoeconomics in hematology treatments. Through systematic reviews, Dr. Passos contributes significantly to improving treatment protocols and optimizing healthcare resources in hematology.

Conclusion

Dr. Passos is a strong candidate for the Best Researcher Award due to her sustained clinical research, leadership in pediatric hematology, and active involvement in cutting-edge stem cell therapy research.

Publication Top Notes

  • Cost‐Effectiveness of Preemptive Plerixafor Versus Rescue Plerixafor for Mobilization and Collection of Hematopoietic Stem Cells in Patients With Multiple Myeloma and Lymphoma
  • Economic evaluation of plerixafor addition in the mobilization and leukapheresis of hematopoietic stem cells for autologous transplantation: a systematic review