Hu Zhou | Hematology | Excellence in Research Award

Prof. Dr. Hu Zhou | Hematology | Excellence in Research Award

Henan Cancer Hospital | China

Prof. Dr. Hu Zhou is a leading hematology researcher recognized for his extensive work on the pathogenesis and clinical management of blood disorders, particularly immune thrombocytopenia, myelodysplastic syndromes, myeloproliferative neoplasms, and thrombosis–hemostasis abnormalities. With 621 citations, 78 published documents, and an h-index of 14, he has established a strong scholarly footprint in clinical and translational hematology. His research integrates clinical trials, molecular pathology, and mechanistic studies, contributing significantly to advances in immunoglobulin therapies, monoclonal antibodies, JAK2 inhibitors, and recombinant thrombopoietic agents. He has illuminated genetic polymorphisms, cytokine signaling pathways, and immune dysregulation mechanisms underlying chronic immune thrombocytopenia. His contributions further extend to leukemogenesis, epigenetic alterations in hematologic malignancies, and therapeutic optimization in refractory leukemia. As an active member of national and international hematology societies, he leads major funded research projects and has been recognized with multiple scientific achievement awards, reflecting his broad impact on hematologic innovation and patient-centered clinical advancement.

Profile: Scopus

Featured Publications

1. Zhou, H., et al. (2025). Efficacy and safety of a new 10% intravenous immunoglobulin (IVIG) in Chinese patients with primary immune thrombocytopenia (ITP): A multicenter, single-arm, phase III trial. Clinical and Experimental Medicine.

2. Zhou, H., et al. (2025). Anti-CD38 monoclonal antibody CM313 for primary immune thrombocytopenia: Multicentre, randomised, placebo-controlled, phase 2 trial. BMJ Clinical Research Edition.

3. Zhou, H., et al. (2025). Efficacy and safety of OB756 (a novel selective JAK2 inhibitor) for essential thrombocythemia in patients intolerant of or resistant to hydroxyurea or intolerant of interferon: A phase 2, open-label, multicenter study. Cancer.

4. Zhou, H., et al. (2025). Hetrombopag for patients with persistent primary immune thrombocytopenia: A post hoc analysis of a multicenter, randomized phase III trial. Research and Practice in Thrombosis and Haemostasis.

5. Zhou, H., et al. (2025). Dose-optimised recombinant human thrombopoietin versus eltrombopag in patients with immune thrombocytopenia: A multicenter, randomised controlled trial (The TE-ITP Study). EClinicalMedicine.

Bing Xiu | Hematology | Best Researcher Award

Prof. Bing Xiu | Hematology | Best Researcher Award

Prof. Bing Xiu | Tongji University | China 

Prof. Bing Xiu is an esteemed Associate Chief Physician and Vice Professor at the Department of Hematology, Tongji Hospital, Tongji University, Shanghai, China. With over two decades of experience in hematology, she holds a Ph.D. in Internal Medicine and has undertaken advanced training at the Mayo Clinic, USA. Prof. Xiu is a certified specialist in internal medicine and hematology and serves as a Master’s supervisor. Her research focuses on lymphoma, T-cell exhaustion, immunotherapy, and CAR-T related cytokine release syndrome. She has led and contributed to several major national and international research projects, including those funded by the NSFC and NIH. Prof. Xiu has published extensively in high-impact journals like Blood Cancer Journal, Leukemia, and Clinical Cancer Research, and has presented at ASH and ASCO, earning abstract honors. She also co-edited a clinical dataset book on diffuse large B-cell lymphoma and is active in several national medical associations and academic committees.

Publication Profile

Scopus

Education Background

Prof. Bing Xiu has pursued her entire medical education at the prestigious Medical College of Tongji University in Shanghai, China, demonstrating a consistent commitment to academic excellence and specialization in internal medicine. She began her journey in medicine by earning her Bachelor of Medicine degree from Tongji University, where she laid the foundational knowledge in clinical sciences. Her passion for hematology and internal medicine led her to further academic pursuit, completing her Master of Medicine from the same institution. With an increasing focus on clinical research and advanced therapeutics, Prof. Xiu earned her Ph.D. in Internal Medicine from Tongji University, focusing on cutting-edge areas of hematologic malignancies. This continuous and progressive educational pathway has equipped her with deep theoretical knowledge and advanced research capabilities that have significantly influenced her medical and academic career.

Professional Experience

Prof. Bing Xiu has built a distinguished career in hematology through extensive clinical, academic, and international experience. She serves as the Associate Chief Physician in the Department of Hematology at Tongji Hospital, Tongji University, Shanghai, where she also holds the role of Master’s supervisor. Her international exposure includes prestigious appointments as a Research Fellow and Visiting Clinician at the Mayo Clinic, Rochester, USA. Prof. Xiu’s earlier roles at Tongji Hospital include her tenure as a Fellow and as a Resident, marking a steady progression in her professional responsibilities. This rich blend of domestic and international clinical research and patient care has shaped her into a leader in hematology and academic mentorship.

Professional Certifications

Prof. Bing Xiu holds esteemed certifications that underscore her clinical expertise and professional standing in the field of internal medicine and hematology. She is certified by the Chinese Board of Internal Medicine, which affirms her comprehensive proficiency in diagnosing and managing a wide range of medical conditions. In addition, she possesses a specialized certification in Internal Medicine-Hematology from the same board, highlighting her focused expertise in the diagnosis and treatment of blood disorders, hematologic malignancies, and related immunological conditions. These dual certifications not only reflect her advanced clinical training but also qualify her to deliver high-level patient care, contribute to academic leadership, and mentor postgraduate students in hematology. Recognized by national regulatory authorities, these credentials form the foundation of her credibility and professionalism in China’s medical and academic community, supporting her roles in major research projects, teaching, and leadership in national medical societies.

Research Focus

Prof. Bing Xiu focuses her research on the molecular and translational mechanisms underlying hematologic malignancies, with particular emphasis on lymphomas and myeloproliferative neoplasms. Her recent publications explore critical areas such as germline mutations in lymphoma-associated hemophagocytic lymphohistiocytosis (LA-HLH), indicating an interest in immune dysregulation and genetic predisposition in aggressive B-cell lymphomas. She has also investigated epigenetic and genetic alterations, such as single nucleotide polymorphisms and promoter methylation of protein tyrosine phosphatase 1B, in myeloproliferative disorders, showcasing her engagement in cancer genomics. Furthermore, her research integrates cutting-edge immunotherapies, including CAR T-cell therapy combined with autologous hematopoietic cell transplantation for refractory/relapsed Burkitt lymphoma, indicating her commitment to improving outcomes through personalized and cellular therapies. Collectively, her work lies at the intersection of cancer genetics, immunotherapy, and translational hematology, making significant contributions to advancing targeted and immune-based treatments for hematologic cancers.

Publication Top Notes

1. Germline mutations in B-cell non-Hodgkin lymphoma-associated hemophagocytic lymphohistiocytosis (LA-HLH) and patient outcomes
Publication Year: 2025

2. Single nucleotide polymorphism and promoter methylation analysis of protein tyrosine phosphatase 1B in patients with myeloproliferative neoplasms
Publication Year: 2025

3. CAR T-cell therapy combined with autologous hematopoietic cell transplantation in patients with refractory/relapsed Burkitt Lymphoma
Publication Year: 2025
Citations: 1

Conclusion

Prof. Bing Xiu is highly suitable for the Best Researcher Award. Her record combines clinical excellence, high-impact hematological research (particularly in lymphoma and immunotherapy), international collaboration, grant leadership, and academic publishing. With a few more translational innovations or expanded global leadership, she would stand at the pinnacle of international medical research. As it stands, she is a top-tier candidate whose body of work exemplifies the award’s purpose to honor groundbreaking research with societal and scientific relevance.

 

 

Betty Pace | Hematology | Best Researcher Award

Dr. Betty Pace | Hematology | Best Researcher Award

Dr. Betty Pace, Augusta University, United States

Dr. Betty Sue Pace, MD, is a Professor with tenure at Augusta University, serving in the Departments of Pediatrics and Biochemistry & Molecular Biology. 🧬 She holds the prestigious Francis J. Tedesco Distinguished Chair in Pediatric Hematology/Oncology and is a member of the Georgia Cancer Center. 🌟 With a medical degree from the Medical College of Wisconsin and postdoctoral training at the University of Washington, Dr. Pace is a leader in sickle cell disease research. ❤️ She has directed major research centers and served on national committees, including NIH and ASH. 📚 Her work promotes diversity, inclusion, and scientific advancement.

Publication Profile

Scopus

🎓 Education & Training

Dr. Betty Sue Pace began her academic journey at Lake Forest College in 1973, later earning her B.S. in Mathematics from Marquette University in 1976. ➗ She pursued her M.D. in Medicine at the Medical College of Wisconsin, graduating in 1981. 🩺 Dr. Pace completed her Pediatric Internship and Residency (1981–1984) at the same institution’s Children’s Hospital. 👶 She further specialized through a Pediatric Hematology/Oncology Fellowship at the University of Colorado Health Sciences Center (1987–1990). 🧬 In 1990, she briefly served as a Locum Tenens Pediatrician before undertaking a Postdoctoral Research Fellowship at the University of Washington (1990–1994).

🏅 Awards & Honors

Dr. Betty Sue Pace has received numerous prestigious accolades throughout her career. 🌟 In 1981, she was honored with the Kaiser Foundation Merit Award, Mosby Mirror Award, and Alpha Omega Alpha induction. 🏆 A Harold Amos Scholar in 1990, she was later named among Popular Science’s “Brilliant 10” in 2003. 🧪 Her work earned her Lifetime Achievement (2007), Diversity Champion (2010), and Distinguished Researcher (2022) awards. 💼 She also established endowed scholarships in her name and currently serves as Editor-in-Chief of the Journal of Sickle Cell Disease (2025). 📰 Her honors reflect a legacy of excellence in science, service, and inclusion.

Research Focus

Dr. Betty S. Pace’s research is primarily centered on sickle cell disease (SCD), with a strong focus on oxidative stress, fetal hemoglobin induction, and gene regulation. 🧬 Her work explores epigenetic therapies, histone deacetylase inhibitors, and NRF2 activation to mitigate disease symptoms. 🧫 She utilizes transgenic models, CRISPR techniques, and microRNA therapies to induce fetal hemoglobin expression and reduce ferroptosis. 💉 Her interdisciplinary research bridges molecular biology, hematology, and genomic innovation, aiming to develop novel therapeutic strategies for SCD. 🧠 Through collaborative studies and translational science, she is advancing curative solutions and improving patient outcomes worldwide.

Publication Top Notes

📄 “Transsulfuration pathway activation attenuates oxidative stress and ferroptosis…”Communications Biology, 2025 | Cited by: 1 📚🧬

📄 “CT-101 flips the switch to fetal hemoglobin expression…”PLOS One, 2025 🧪🧬

📄 “Innovations in Drug Discovery for SCD Targeting Oxidative Stress and NRF2…”Review, 2025  💊🧠

📄 “Endothelial ENaC-a Restrains Oxidative Stress in Lung Capillaries…”Am J Respir Cell Mol Biol, 2025 | Cited by: 2 🫁🔬

📄 “Hematopoietic cell transplant vs standard care in adolescents…”Blood Advances, 2025  🧫🧒

📄 “miR-29b induces fetal haemoglobin via promoter demethylation…”Br J Haematol, 2025 🧬🧠

📄 “Correction to: CRISPR-mediated fetal chromatin domain ablations”Scientific Reports, 2022  🧪📘

📄 “Telehealth Use Among People with SCD During COVID-19…”Telemedicine & e-Health, 2024 | Cited by: 1 💻📞

📄 “Simvastatin-Mediated Nrf2 Activation in SCD Mice…”Antioxidants, 2024 | Cited by: 2 🧬🛡️

📄 “Emergency Department Visits by Individuals With SCD (1999–2020)…”Ajpm Focus, 2024 | Cited by: 6 🏥📈