Hatice Yesim Karasulu | Pharmacology | Excellence in Research

Prof Hatice Yesim Karasulu, Ege University, Turkey

Prof. Dr. Hatice Yesim Karasulu is a renowned pharmaceutical technology expert at Ege University, Turkey. With a Ph.D. in Pharmaceutical Technology, she became an Associate Professor in 2006 and a Professor in 2011. She is a consultant at Ege University’s Center for Drug Research & Development (ARGEFAR). Dr. Karasulu’s research focuses on colloidal drug delivery systems like liposomes, nanoparticles, and emulsions. She has over 50 publications, 2 patents, and several industry collaborations. Additionally, she has authored multiple book chapters and received various grants. 🌍💊📚🔬💡

Publication Profile

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Academic and Professional Background

Prof. Dr. Hatice Yesim Karasulu is a renowned academic and consultant in pharmaceutical technology. With a Ph.D. from the University of Ege, she became an Associate Professor in 2006 and a Professor in 2011. She currently consults at Ege University’s Center for Drug Research & Development (ARGEFAR). Dr. Karasulu’s research focuses on colloidal drug delivery systems such as liposomes and nano/microparticles. She has published over 50 papers, authored five book chapters, and holds two patents related to nano-drug delivery systems. Her collaborative projects with universities and the pharmaceutical industry aim to innovate drug delivery. 🧪📚

Research and Innovations

Prof. Hatice Yesim has conducted extensive research on drug delivery systems, particularly through EU and TUBITAK-funded projects. Her studies focus on the development of microemulsion formulations, bioadhesive systems, and surfactant effects for enhanced drug bioavailability. Notable projects include investigations on skin absorption, nasal drug diffusion, and the creation of transdermal systems for various drugs such as naproxen and terbutaline sulphate. Additionally, Prof. Yesim has explored the use of PEG-PLA-PGA triblock micelles for cancer treatments and innovative dry powder inhalers for asthma management. Her work contributes significantly to improving drug delivery technologies for targeted therapies. 🌟👩‍🔬

Books and Patents

Prof. Hatice Yesim Karasulu is a distinguished academic and researcher, known for her contributions to pharmaceutical sciences. As an author of several influential book chapters, she has published with leading publishers like Elsevier, Taylor & Francis, and InTech. Prof. Karasulu holds multiple patents, including innovative nano-drug delivery systems, with both national and international applications. Her work exemplifies a seamless integration of cutting-edge research and practical solutions, especially in the pharmaceutical industry. Her contributions continue to impact the development of new drug delivery technologies. 📚💡💊🌍

Industry Projects

Prof. Hatice Yesim’s research focuses on the development of products aimed at improving the quality of life for psoriasis patients. Her work involves conducting clinical trials and preparing submissions for approval, such as those to the Ministry of Health in CTD format. The primary goal of her research is to create effective solutions for managing psoriasis, a chronic skin condition, and to enhance patient outcomes through innovative treatments. This aligns with areas of dermatology, clinical trials, and health innovation. Her research significantly contributes to improving patient care and advancing medical treatments for dermatological conditions. 🧴🩺💊🧑‍🔬

Research Focus

Prof. Hatice Yesim Karasulu’s research focuses on pharmaceutical formulations and drug delivery systems, with a particular emphasis on transdermal delivery, microemulsions, and lipophilic microspheres. Her work explores the skin permeation, anti-inflammatory effects, and analgesic properties of various formulations like diclofenac sodium and naproxen. She has also studied the toxicity, stability, and applications of microemulsions as novel drug carriers. Additionally, her research includes the pharmacokinetics of drugs, modeling drug release, and the use of bioadhesive formulations in vaginal and nasal drug delivery systems. 💊📦💉💡🌱

Publication Top Notes

Transdermal delivery of diclofenac sodium through rat skin from various formulations

Evaluation of skin permeation and anti-inflammatory and analgesic effects of new naproxen microemulsion formulations

Microemulsions as novel drug carriers: the formation, stability, applications and toxicity

Comparison of different water/oil microemulsions containing diclofenac sodium: preparation, characterization, release rate, and skin irritation studies

Extended release lipophilic indomethacin microspheres: formulation factors and mathematical equations fitted drug release rates

Modeling of theophylline release from different geometrical erodible tablets

Efficacy of a new ketoconazole bioadhesive vaginal tablet on Candida albicans

Prof. Fatmah Alasmary | Pharmaceutical innovation | Best Researcher Award

Prof. Fatmah Alasmary, Saudi Food and Drug Authority, Saudi Arabia

Professor at King Saud University, specializing in organic chemistry. Dr. Alasmary has extensive experience in academia and leadership, with a PhD from the University of Bradford. Currently, she serves as Director of the Drug Lab at the Saudi Food and Drug Authority. Her research interests include antimicrobial agents and nanomaterials. Dr. Alasmary has mentored numerous students and has held key roles in various scientific committees. She is a member of the Saudi Chemical Association, the Royal Society of Chemistry, and the American Chemical Society. 🧑‍🔬👩‍🏫🔬

Work Experience 🌍💼

Prof. Fatmahalasmary is a distinguished academic and professional, currently serving as the Director of Drug Lab at Saudi Food and Drug Authority, Riyadh. She oversees quality control, safety standards, and international accreditation efforts for medicines and cosmetics. As Chief of Senior Expert International Communication, she leads food standards initiatives for Saudi Arabia, managing ISO committees and Codex committees. Previously, she was Vice Chairman at King Saud University’s Chemistry Department, coordinating research, teaching, and international collaborations. Prof. Fatmahalasmary’s leadership spans teaching, curriculum development, and guiding postgraduate research, exemplifying excellence in both academic and professional spheres. 📚🌐👩‍🔬

Qualifications 🎓🌟

Prof. Fatmahalasmary holds a PhD in Chemistry from the University of Bradford, England (2013), where her thesis focused on the synthesis and evaluation of benzimidazole derivatives as potential antimicrobial agents. She earned a Master of Science in Chemistry from King Saud University, KSA (2008), with a thesis on the synthesis and study of quinoxaline derivatives. Additionally, she completed her Bachelor of Science in Chemistry at King Saud University, KSA (2001), graduating with honors. Her academic journey highlights a strong foundation in chemistry and a commitment to research excellence. 🧪📘👩‍🔬

Additional Experience 🌍🔬

Prof. Fatmahalasmary has actively participated in over 22 workshops focused on management, planning, and quality development. She is a member of several prestigious associations, including the Saudi Chemical Association, Royal Society of Chemistry, and American Chemical Society. Her roles have included coordinating committees at King Saud University (KSU), such as the Development and Quality Committee and Labs Committee. Prof. Fatmahalasmary has also been involved in thesis defenses, scientific symposia, and national exhibitions. She holds patents for innovative extracts and is certified in ISO 9001:2015 and as a Certified Innovation Professional. 📚💡📈

Research Focus

Prof. Fatmah Ali S Alasmary’s research spans various fields, including antimicrobial agents 🦠, biological chemistry 🧬, and medicinal chemistry 💊. She has contributed significantly to the development of benzimidazole derivatives as potential antimicrobial agents, as well as carbonic anhydrase inhibitors targeting various pathogens. Her work also delves into perovskite materials 🏗️, photocatalysis ⚛️, and nanomaterials 🧪 with applications in sensing and biomedical fields. Prof. Alasmary has been actively involved in computational studies of drug design 💻, enzyme inhibition 🧪, and therapeutic applications for diseases like malaria and cancer.

Publication Top Notes

Tin versus lead redox chemistry modulates charge trapping and self-doping in tin/lead iodide perovskites (186 citations, 2020) 🔋
Synthesis and evaluation of selected benzimidazole derivatives as potential antimicrobial agents (140 citations, 2015) 💊
Inhibition of the β-carbonic anhydrase from the dandruff-producing fungus Malassezia globosa with monothiocarbamates (41 citations, 2017) 🦠
Direct Access to α‐Aminosilanes Enabled by Visible‐Light‐Mediated Multicomponent Radical Cross‐Coupling (36 citations, 2021) 💡
Development of certain novel N-(2-(2-(2-oxoindolin-3-ylidene)hydrazinecarbonyl)phenyl)-benzamides and 3-(2-oxoindolin-3-ylideneamino)-2-substituted quinazolin-4(3 H)-ones as … (35 citations, 2015) 🔬
Analysis of Alpina officinarum Hance, chemically and biologically (30 citations, 2019) 🌿
Combined computational and experimental investigation on the nature of hydrated iodoplumbate complexes: Insights into the dual role of water in perovskite precursor solutions (28 citations, 2020) 💧
The first activation studies of the η-carbonic anhydrase from the malaria parasite Plasmodium falciparum with amines and amino acids (28 citations, 2018) 🦠
New quinoxalinone inhibitors targeting secreted phospholipase A2 and α-glucosidase (28 citations, 2017) 🧪
Structure-based identification of SARS-CoV-2 main protease inhibitors from anti-viral specific chemical libraries: an exhaustive computational screening approach (27 citations, 2021) 🦠