Dr Zhenhan Deng, The First Affiliated Hospital of Wenzhou Medical University, China
Dr. Zhenhan Deng is a distinguished orthopedic surgeon born on July 19, 1989. He currently serves as a Deputy Chief Physician at The First Affiliated Hospital of Wenzhou Medical University in China ๐จ๐ณ. Dr. Deng completed his Ph.D. at Xiangya Hospital, CSU, and was a visiting scholar at the University of Texas Health Science Center ๐ฅ. His research focuses on osteoarthritis and cartilage regeneration, supported by significant grants and notable publications ๐. He has received multiple awards, including the Orthopaedic Research Society’s New Investigator Recognition Award and the Shenzhen Health Elite Talent title ๐. For more details, visit his official website ๐.
Publication profile
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Education
Deng pursued his Ph.D. in Orthopedics at Xiangya Hospital, Central South University (CSU), Hunan, China, from September 2015 to November 2018. Additionally, he was a Visiting Scholar at the University of Texas Health Science Center at Houston, focusing on Orthopedics, from December 2016 to September 2018. Prior to his doctoral studies, Deng completed his Master of Medicine and Bachelor of Medicine degrees at Xiangya Hospital, CSU.
Work Experience
Throughout his career, Deng has held various positions in orthopedic surgery and sports medicine. He served as a Deputy Chief Physician in the Department of Orthopedic Surgery at The First Affiliated Hospital of Wenzhou Medical University from December 2023 to September 2023. Prior to this, he worked as an Attending Physician in the same department. Deng also gained experience as an Attending Physician in the Department of Sports Medicine at Shenzhen Second People’s Hospital, Shenzhen, Guangdong, China, from September 2020 to September 2023, after starting as a Resident Physician in December 2018.
Awards
Deng has received numerous awards and honors for his contributions to orthopedic research and clinical practice. Notable accolades include being nominated for the Orthopaedic Research Society (ORS) New Investigator Recognition Awards (NIRA), winning the Orthopaedic Research Society (ORS) ON Foundation/ORS Orthoregeneration Award, and receiving recognition as an Outstanding Graduate of Hunan Province.
Research focus
Zhenhan Deng is an orthopaedic surgeon and researcher focused on advancing treatments for musculoskeletal conditions, particularly osteoarthritis and cartilage repair. His research encompasses the development of innovative therapies, such as microgel scaffolds, mesenchymal stem cells, and gene therapy to promote cartilage regeneration and joint repair. Dengโs work includes investigating the roles of various signaling pathways in disease progression and treatment efficacy. His projects and publications underscore his commitment to improving patient outcomes through cutting-edge, translational medical research. ๐ฉบ๐ฆด๐งฌ๐ฌ๐ก๐
For further information, you can visit his personal work website at https://dzhdr.haodf.com/.
Publication top notes
- Electrical stimulation for pain relief in knee osteoarthritis: systematic review and network meta-analysis
C Zeng, T Yang, Z Deng, Y Yang, Y Zhang, G Lei
Osteoarthritis and Cartilage, 2015 – 179 citations ๐
- Effectiveness of continuous and pulsed ultrasound for the management of knee osteoarthritis: a systematic review and network meta-analysis
C Zeng, H Li, T Yang, ZH Deng, Y Yang, Y Zhang, X Ding, GH Lei
Osteoarthritis and Cartilage, 2014 – 158 citations ๐
- Macrophages in osteoarthritis: pathophysiology and therapeutics
Y Chen, W Jiang, H Yong, M He, Y Yang, Z Deng, Y Li
American Journal of Translational Research, 2020 – 118 citations ๐ฆ
- Bone morphogenetic proteins for articular cartilage regeneration
ZH Deng, YS Li, X Gao, GH Lei, J Huard
Osteoarthritis and Cartilage, 2018 – 103 citations ๐
- The role of sirtuin 1 and its activator, resveratrol in osteoarthritis
Z Deng, Y Li, H Liu, S Xiao, L Li, J Tian, C Cheng, G Zhang, F Zhang
Bioscience Reports, 2019 – 97 citations ๐
- Long noncoding RNAs in osteoarthritis
J Lu, Z Deng, Y Li, G Lei
Joint Bone Spine, 2017 – 88 citations ๐งฌ
- Cartilage tissue engineering: From proinflammatory and antiโinflammatory cytokines to osteoarthritis treatments
S Liu, Z Deng, K Chen, S Jian, F Zhou, Y Yang, Z Fu, H Xie, J Xiong, …
Molecular Medicine Reports, 2022 – 86 citations ๐ฆด
- Is posterior tibial slope associated with noncontact anterior cruciate ligament injury?
C Zeng, T Yang, S Wu, S Gao, H Li, Z Deng, Y Zhang, G Lei
Knee Surgery, Sports Traumatology, Arthroscopy, 2016 – 81 citations ๐โโ๏ธ
- Characterization of a novel polyvinyl alcohol/chitosan porous hydrogel combined with bone marrow mesenchymal stem cells and its application in articular cartilage repair
L Peng, Y Zhou, W Lu, W Zhu, Y Li, K Chen, G Zhang, J Xu, Z Deng, …
BMC Musculoskeletal Disorders, 2019 – 73 citations ๐ง
- Association between dietary magnesium intake and radiographic knee osteoarthritis
C Zeng, H Li, J Wei, T Yang, Z Deng, Y Yang, Y Zhang, T Yang, G Lei
PLoS One, 2015 – 70 citations ๐ฝ๏ธ
- RhoA/ROCK pathway: implication in osteoarthritis and therapeutic targets
Z Deng, Y Jia, H Liu, M He, Y Yang, W Xiao, Y Li
American Journal of Translational Research, 2019 – 67 citations ๐ฌ
- MALAT1 promotes osteosarcoma development by targeting TGFA via MIR376A
W Luo, H He, W Xiao, Q Liu, Z Deng, Y Lu, Q Wang, Q Zheng, Y Li
Oncotarget, 2016 – 65 citations ๐ฏ
- Alterations of amino acid metabolism in osteoarthritis: its implications for nutrition and health
Y Li, W Xiao, W Luo, C Zeng, Z Deng, W Ren, G Wu, G Lei
Amino Acids, 2016 – 63 citations ๐ฝ๏ธ
- Modified arthroscopic Latarjet procedure: suture-button fixation achieves excellent remodeling at 3-year follow-up
J Xu, H Liu, W Lu, Z Deng, W Zhu, L Peng, K Ouyang, H Li, D Wang
The American Journal of Sports Medicine, 2020 – 58 citations ๐
- MicroRNA-199a-5p inhibits cisplatin-induced drug resistance via inhibition of autophagy in osteosarcoma cells
Y Li, W Jiang, Y Hu, Z Da, C Zeng, M Tu, Z Deng, W Xiao
Oncology Letters, 2016 – 53 citations ๐ซ
- MicroRNA-379 inhibits the proliferation, migration and invasion of human osteosarcoma cells by targetting EIF4G2
X Xie, YS Li, WF Xiao, ZH Deng, HB He, Q Liu, W Luo
Bioscience Reports, 2017 – 51 citations ๐ก๏ธ
- MicroRNA-127-5p regulates osteopontin expression and osteopontin-mediated proliferation of human chondrocytes
M Tu, Y Li, C Zeng, Z Deng, S Gao, W Xiao, W Luo, W Jiang, L Li, G Lei
Scientific Reports, 2016 – 50 citations ๐งซ
- p38MAPK signaling pathway in osteoarthritis: pathological and therapeutic aspects
Z Li, A Dai, M Yang, S Chen, Z Deng, L Li
Journal of Inflammation Research, 2022 – 45 citations ๐ก๏ธ
- Diet-intestinal microbiota axis in osteoarthritis: a possible role
Y Li, W Luo, Z Deng, G Lei
Mediators of Inflammation, 2016 – 45 citations ๐
- Relationship between cigarette smoking and radiographic knee osteoarthritis in Chinese population: a cross-sectional study
Y Zhang, C Zeng, H Li, T Yang, Z Deng, Y Yang, X Ding, D Xie, Y Wang, …
Rheumatology International, 2015 – 45 citations ๐ฌ
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