Dr. James Goldenring | Gastroenterology | Best Researcher Award
Dr. James Goldenring, Vanderbilt University Medical Center, United States
Dr. James Goldenring is an accomplished physician-scientist with an M.D. and Ph.D. in Molecular Biophysics and Biochemistry from Yale University. His research focused on calmodulin-dependent kinase and molecular signaling. Currently serving as the Scientific Director at Vanderbilt University School of Medicine, he co-directs the Epithelial Biology Center. With extensive experience, he holds the Paul W. Sanger Chair and is a Professor of Cell and Developmental Biology. Dr. Goldenring has contributed significantly as Chief of Cell Signaling at the Medical College of Georgia and as a Research Health Specialist at the Nashville VA Medical Center. 🧪🔬
Publication Profile :
Education :
Dr. James Goldenring is a distinguished physician-scientist, earning his M.D. from Yale University School of Medicine in May 1986. He furthered his academic journey with a Ph.D. in Molecular Biophysics and Biochemistry from Yale, completing his dissertation on the purification and distribution of a calmodulin-dependent kinase from rat brain, under the guidance of advisor Robert J. DeLorenzo, MD, PhD. Dr. Goldenring obtained an M.Phil. in Molecular Biophysics and Biochemistry from Yale in May 1984. Graduating Magna Cum Laude from Harvard University in June 1980 with an A.B. in Biochemical Sciences, his thesis explored the impact of artificial food dyes on the developing nervous system. Advisors Bennett A. Shaywitz, MD, and Ronald Harris-Warwick, PhD, played crucial roles in shaping his early research. 🎓🔬
Experience :
Dr. James Goldenring boasts a prolific career in medical and academic leadership. Currently serving as the Scientific Director at Vanderbilt University School of Medicine since 2013, he oversees the Translational Pathology and Digital Histology Shared Resources. As Co-Director of the Epithelial Biology Center since 2008, he contributes significantly to research and innovation. Holding the Paul W. Sanger Chair, he is Professor and Vice Chairman for Surgical Research, as well as a Professor of Cell and Developmental Biology at Vanderbilt since 2002. Dr. Goldenring’s extensive experience spans roles such as Chief of the Program in Cell Signaling at the Medical College of Georgia and leadership positions at the Augusta VA Medical Center. His journey began at Yale University School of Medicine, where he served as a Resident, Postdoctoral Associate, and Assistant Professor. 🏥🔍
Honors:
Dr. James Goldenring has garnered numerous accolades for his outstanding contributions to medical science. Notable honors include the AGA Distinguished Achievement Award in Basic Science (2023), the Horace Davenport Distinguished Lectureship from the American Physiological Society (2023), and the J.S. Min Memorial Lecture at the Korea International Gastric Cancer Association (2022). Recognized for collaborative efforts, he received the John A. Oates Award at Vanderbilt University Medical Center in 2021. His achievements also encompass the Takeda Distinguished Research Award (2011) and the AGA Institute Council Cellular and Molecular Gastroenterology Research Mentor Award (2016). Dr. Goldenring’s illustrious career is marked by prestigious fellowships, scholarships, and leadership in gastric biology research. 🏆🔬
Certification:
Dr. James Goldenring holds vital certifications affirming his medical expertise. With National Board of Medical Examiners certification (No. 297811), he demonstrates comprehensive knowledge in medical disciplines. His Connecticut State Medical License (No. 029226) underscores his official recognition to practice in the state. Similarly, his Georgia State Medical License (No. 37547) signifies compliance with the state’s medical standards. These certifications, reflective of his commitment to excellence, authorize Dr. Goldenring to contribute to medical advancements and patient care, showcasing a dedication to professional competence and adherence to regulatory standards. 🩺📜
Research Focus:
Dr. James Goldenring’s prolific research focuses on gastrointestinal physiology and cancer, marked by groundbreaking contributions to understanding gastric cancer development. His work includes seminal studies on the role of bone marrow-derived cells in gastric cancer (Science, 2004) and the synergistic interaction between hypergastrinemia and Helicobacter infection (Gastroenterology, 2000). Pioneering roles of Sox2 in foregut endoderm patterning (Development, 2007) and the identification of Myosin Vb in plasma membrane recycling (Molecular Biology of the Cell, 2001) exemplify his diverse interests. Dr. Goldenring’s impactful research encompasses molecular mechanisms, cellular interactions, and disease pathways in the gastrointestinal system, contributing significantly to medical science. 🧪🔬
Publication Top Notes :
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Gastric cancer originating from bone marrow-derived cells 📚 Cited by 1603 (2004)
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Synergistic interaction between hypergastrinemia and Helicobacter infection in a mouse model of gastric cancer 📚 Cited by 663 (2000)
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Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm 📚 Cited by 583 (2007)
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Myosin vb is associated with plasma membrane recycling systems📚 Cited by 504 (2001)
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Association of Rab25 and Rab11a with the apical recycling system of polarized Madin–Darby canine kidney cells📚 Cited by 469 (1999)
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Purification and characterization of a calmodulin-dependent kinase from rat brain cytosol able to phosphorylate tubulin and microtubule-associated proteins. 📚 Cited by 388 (1983)
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Ezrin is a cyclic AMP-dependent protein kinase anchoring protein 📚 Cited by 366 (1997)
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Rab11 family interacting protein 2 associates with Myosin Vb and regulates plasma membrane recycling 📚 Cited by 351 (2002)
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Identification and characterization of a family of Rab11-interacting proteins📚 Cited by 336 (2001)
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Targeted disruption of the Kvlqt1 gene causes deafness and gastric hyperplasia in mice 📚 Cited by 336 (2000) 🧪🔬