Prof. Xaio-Lian Zhang at Wuhan University, China
Dr. Xiao-Lian Zhang 🎓 is the Hongyi and Luojia Distinguished Professor and Chair of Immunology at Wuhan University 🧬. A leading expert in infection, glyco-immunity, and vaccine development 💉, she focuses on immune evasion by Mycobacterium tuberculosis and Hepatitis C/B viruses 🦠. With a PhD from HKUST and postdoc at the University of Maryland , she has published 190+ papers in top journals 📚 and holds 46 patents 🧪. A recipient of China’s Outstanding Young Scientist Fund 🌟, her innovative research in intracellular pathogens and glycan-targeted therapies has been globally recognized and ranked in the top 2% by Faculty of 1000 🌍.
Publication Profile📚
Orcid
Academic Background🎓
Dr. Xiao-Lian Zhang 🎓 earned her PhD in Biochemistry from the Hong Kong University of Science and Technology (1993–1997) and completed her postdoctoral training at the University of Maryland, USA (1997–2001). She is currently the Hongyi and Luojia Distinguished Professor and Chair of Immunology at Wuhan University 🧬. Her research focuses on infection, glyco-immunity, and vaccine development 💉, especially against Mycobacterium tuberculosis and Hepatitis B/C viruses 🦠. With over 190 publications 📚, 46 patents 🧪, and numerous national awards 🌟, her work ranks in the top 2% globally 🌍 for its impact and innovation.
Professional background💼
Dr. Xiao-Lian Zhang 💼 is a Hongyi and Luojia Distinguished Professor at Wuhan University and serves as the Chair of the Immunology Department 🧬. She also leads the Hubei Provincial Key Laboratory of Allergic and Immune-related Diseases 🔬. Her research expertise includes infection, glyco-immunity, immune evasion, and vaccine development 💉, particularly targeting Mycobacterium tuberculosis and Hepatitis B/C viruses 🦠. She has led major national programs such as the 973 Program and received the National Outstanding Young Scientist Fund 🌟. With over 190 top-tier publications 📚 and 46 granted patents 🧪, she is recognized globally 🌍 for scientific excellence.
Awards and Honors🏅
Dr. Xiao-Lian Zhang 🏅 has received numerous prestigious awards for her outstanding contributions to biomedical research 🌟. She is a recipient of the National Outstanding Young Scientist Fund 🧬 and was selected for China’s “New Century” National Talent Program . As a Hongyi and Luojia Distinguished Professor, she also leads national-level research projects including the 973 Program and Major Infectious Disease Initiatives 🧪. Her innovative work in infection and glyco-immunity has earned over 190 publications 📚 and global recognition, ranking her among the top 2% of scientists worldwide 🌍 according to Faculty of 1000 🏆.
Research Focus🔬
Dr. Xiao-Lian Zhang 🔬 is a leading researcher in infection and immunity, with a special focus on intracellular pathogens like Mycobacterium tuberculosis and Hepatitis B/C viruses 🦠. Her groundbreaking work explores glyco-immunity, immune evasion mechanisms, and the development of glycan-targeted vaccines, drugs, and diagnostics 💉🧪. She has pioneered novel approaches in immunotherapy and molecular diagnostics, enhancing both understanding and treatment of infectious diseases 🧬. Her research has been published in prestigious journals 📚 and frequently cited in leading reviews, earning her recognition among the top 2% of global scientists 🌍 for impactful, innovative scientific contributions.
Publication Top Notes🌟
🔬 Mycobacterial EST12 activates a RACK1-NLRP3-gasdermin D pyroptosis-IL-1β immune pathway
Year: 2020 | Published in: Science Advances
🧬 Binding of cellular nucleolin with the viral core RNA G-quadruplex structure suppresses HCV replication
Year: 2019 | Published in: Nucleic Acids Research
🧪 Detection of circulating Mycobacterium tuberculosis specific DNA by droplet digital PCR for vaccine evaluation
Year: 2018 | Published in: Emerging Microbes & Infections
💉 A Single ssDNA Aptamer Binding to Mannose-Capped Lipoarabinomannan Enhances Immunoprotection against TB
Year: 2016 | Published in: JACS
🧫 Knockdown of Mgat5 Inhibits Breast Cancer Cell Growth with Activation of CD4⁺ T Cells and Macrophages
Year: 2015 | Published in: Journal of Immunology
🧬 Aptamer against mannose-capped lipoarabinomannan inhibits Mycobacterium tuberculosis in mice and monkeys
Year: 2014 | Published in: Molecular Therapy
🧪 CFP10 and ESAT6 aptamers as effective Mycobacterial antigen diagnostic reagents
Year: 2014 | Published in: Journal of Infection
🧬 Ficolin-2 inhibits HCV infection, Apolipoprotein E3 mediates viral immune escape
Year: 2014 | Published in: Journal of Immunology
Conclusion
Professor Xiao-Lian Zhang is a globally recognized leader in infection biology, immunology, and vaccine research 🧬🦠. With a PhD from HKUST and postdoctoral training at the University of Maryland , she currently holds prestigious positions as Hongyi and Luojia Distinguished Professor and Chair of Immunology at Wuhan University 💼. Her research on glyco-immunity, intracellular pathogens like Mycobacterium tuberculosis and Hepatitis B/C viruses, and glycan-targeted therapies has led to 190+ high-impact publications 📚 and 46 granted patents 🧪. Widely cited and ranked in the top 2% globally 🌍, she has secured major national grants and made transformative contributions to science, making her a highly deserving candidate for the Best Researcher Award 🏆.