Mohammad Sadegh Taghizadeh | Drug Discovery | Best Researcher Award

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Dr. Mohammad Sadegh Taghizadeh | Drug Discovery | Best Researcher Award

Shiraz University | Iran

Dr. Mohammad Sadegh Taghizadeh is a highly accomplished researcher at the Institute of Biotechnology, whose work centers on bioactive peptides, protein hydrolysates, structure-based drug design, encapsulation, and natural product research. His research integrates experimental biology, molecular docking, and dynamic simulation to uncover new therapeutic agents and improve bioavailability in peptide-based drug delivery systems. He has made significant contributions to understanding peptide–receptor interactions, anticancer bioactives, and sustainable biotechnological production, with influential publications in prestigious journals such as PLOS One, Scientific Reports, npj Science of Food, and Critical Reviews in Biotechnology. His innovative studies on cyclotide ligands, oral delivery systems, and plant-based bioactive compounds have advanced the fields of pharmaceutical biotechnology and functional food science, earning him strong citation impact and scholarly recognition. In addition to his research, Dr. Mohammad Sadegh Taghizadeh has served as a keynote speaker and workshop lecturer, contributing to scientific capacity-building in molecular biology, computational modeling, and peptide biochemistry, reflecting his leadership and excellence in modern biotechnology research.

Profile: Google Scholar

Featured Publications

  • Taghizadeh, M. S., Niazi, A., Moghadam, A., & Afsharifar, A. (2022). Experimental, molecular docking and molecular dynamic studies of natural products targeting overexpressed receptors in breast cancer. PLOS ONE, 17(5), e0267961.

  • Mirzapour-Kouhdasht, A., McClements, D. J., Taghizadeh, M. S., Niazi, A., & others. (2023). Strategies for oral delivery of bioactive peptides with focus on debittering and masking. npj Science of Food, 7(1), 22.

  • Mirzapour-Kouhdasht, A., Sabzipour, F., Taghizadeh, M. S., & others. (2019). Physicochemical, rheological, and molecular characterization of colloidal gelatin produced from common carp by-products using microwave and ultrasound-assisted extraction. Journal of Texture Studies, 50(5), 416–425.

  • Taghizadeh, M. S., Retzl, B., Muratspahić, E., Trenk, C., Casanova, E., & Gruber, C. W. (2022). Discovery of the cyclotide caripe 11 as a ligand of the cholecystokinin-2 receptor. Scientific Reports, 12(1), 9215.

  • Shahraki, Z., Taghizadeh, M. S., Niazi, A., Rowshan, V., & Moghadam, A. (2024). Enhancing bioactive compound production in Salvia mirzayanii through elicitor application: Insights from in vitro and in silico studies. Food Bioscience, 60, 104185.

Xintian Shao | Pharmaceutical Science Award | Best Researcher Award

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Dr. Xintian Shao | Pharmaceutical Science Award | Best Researcher Award

Dr. Xintian Shao, Shandong First Medical University & Shandong Academy of Medical Sciences, China

Dr. Xintian Shao earned her PhD in Microbiology and Biochemical Pharmacy from Shandong University, China, under the guidance of Prof. Peixue Ling. She expanded her expertise as a Visiting Scholar in Cancer Biology at the University of Cincinnati, USA, mentored by Prof. Jiajie Diao. Currently serving as an Associate Professor at Shandong First Medical University, her research has yielded 10 impactful publications and secured numerous grants. With two patents to her name, she’s been honored with prestigious awards including the Shandong Medical Science and Technology Award and the Science and Technology Award of Shandong Pharmaceutical Association.

 

Publication Profile 

Scopus

Education and Academic Achievements 📚🏅

Dr. Xintian Shao completed her PhD in Microbiology and Biochemical Pharmacy at the School of Pharmacy, Shandong University, China, under the guidance of Prof. Peixue Ling. She further enriched her expertise as a visiting scholar in Cancer Biology at the University of Cincinnati, USA, mentored by Prof. Jiajie Diao. Her prolific research has resulted in 10 publications, including notable contributions to journals such as Advanced Drug Delivery Reviews and Advanced Science. With multiple patents and prestigious grants to her credit, she has earned recognition including the Shandong Medical Science and Technology Award (2021) and the Science and Technology Award of Shandong Pharmaceutical Association (2022).

Work Experience 💼

Dr. Xintian Shao has served as an Associate Professor at the School of Life Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, China. Her role involves not only teaching and mentorship but also continued research contributions in her field.

Research Focus

Dr. Xintian Shao’s research primarily focuses on subcellular imaging and targeted drug delivery systems. Her work delves into the intricate dynamics of organelle interactions, particularly within mitochondria and lysosomes, employing cutting-edge super-resolution imaging techniques. She explores novel methods for visualizing drug molecules within living organisms, enhancing our understanding of drug distribution and efficacy. With a keen interest in membrane biology and organelle-specific targeting, her contributions shed light on fundamental cellular processes and hold promise for advancements in drug delivery and therapeutics.

Publication Top Notes 

  1. “Single-organelle localization-based super-resolution imaging for subcellular molecules micro-dynamics” by Fang, G. et al., Coordination Chemistry Reviews, 2024.
  2. “Enhanced optical imaging and fluorescent labeling for visualizing drug molecules within living organisms” by Sun, T. et al., Acta Pharmaceutica Sinica B, 2024.
  3. “Mitochondrial nucleoid condensates drive peripheral fission through high membrane curvature” by Chen, Q. et al., Cell Reports, 2023.
    Cited by: 1
  4. “Graphene Oxide Nanosheets Induce Mitochondrial Fragmentation by Cutting through Membrane” by Shao, X. et al., ACS Materials Letters, 2023.
    Cited by: 4
  5. “Subcellular visualization: Organelle-specific targeted drug delivery and discovery” by Shao, X. et al., Advanced Drug Delivery Reviews, 2023.
    Cited by: 7
  6. “Recent advances in fluorescent probes of peroxynitrite: Structural, strategies and biological applications” by Sun, J. et al., Theranostics, 2023.
    Cited by: 8
  7. “Single Image Capture of Bioactive Ion Crosstalk within Inter-Organelle Membrane Contacts at Nanometer Resolution” by Fang, G. et al., Small Methods, 2022.
    Cited by: 8
  8. “Lysosome-Targeted Biosensor for the Super-Resolution Imaging of Lysosome–Mitochondrion Interaction” by Wang, H. et al., Frontiers in Pharmacology, 2022.
    Cited by: 4
  9. “Super-resolution image-based tracking of drug distribution in mitochondria of a label-free naturally derived drug molecules” by Wei, Y. et al., Chemical Engineering Journal, 2022.
    Cited by: 19
  10. “Prefused lysosomes cluster on autophagosomes regulated by VAMP8” by Chen, Q. et al., Cell Death and Disease, 2021.
    Cited by: 24