Lecturer at Tianjin Medical University, China
Dr. Shan Huang is a Lecturer at the Department of Health Toxicology and Health Inspection & Quarantine, Tianjin Medical University. She holds a Ph.D. in Medical Cell Biology and completed her postdoctoral research in Public Health. Her work focuses on the regulatory mechanisms of innate and adaptive immune responses, with groundbreaking contributions to antiviral immunity and tumor immune evasion. She has published in top journals like Nature Communications and Science Signaling and secured prestigious research grants, including NSFC and China Postdoctoral Science Foundation. Her research advances immunology and molecular biology, impacting disease treatment strategies. ๐๐ฆ โจ
Publication Profile
Scopus
Educational Background ๐๐ฌ
Dr. Shan Huang pursued a B.Eng. in Biomedical Engineering (2009โ2013) from the School of Biomedical Engineering, Tianjin Medical University ๐ฅโ๏ธ, where she developed a strong foundation in medical technology and biological systems. She then earned her Ph.D. in Medical Cell Biology (2014โ2020) from the Department of Medical Cell Biology, Tianjin Medical University ๐งฌ๐, focusing on cellular mechanisms in immunity. Further advancing her expertise, she completed a postdoctoral fellowship in Public Health (2021โ2024) at Tianjin Medical University ๐๏ธ๐ฆ , specializing in immunological responses and disease mechanisms, contributing significantly to cutting-edge biomedical research.
Professional Experience ๐ฉโ๐ซ๐ฌ
Dr. Shan Huang currently serves as a Lecturer (July 2024โpresent) in the Department of Health Toxicology and Health Inspection & Quarantine at the School of Public Health, Tianjin Medical University ๐๏ธ๐ฆ . In this role, she focuses on advancing research in health toxicology, immunology, and disease prevention. Her expertise in antiviral immunity and tumor immune evasion plays a crucial role in educating future researchers and contributing to scientific advancements. Through her teaching and research, Dr. Huang continues to make significant contributions to public health, bridging the gap between biomedical sciences and clinical applications. ๐๐โจ
Research Focus ๐ฌ๐ฆ
Dr. Shan Huang’s research primarily focuses on innate and adaptive immune regulation, antiviral immunity, and tumor immunology ๐งฌ๐ก๏ธ. Her work explores interferon signaling, epigenetic regulation, and immune evasion mechanisms in cancer and viral infections ๐ฆ ๐๏ธ. She investigates how key proteins and pathways, such as MLL4, MAVS, and GSDMD, influence immune responses and disease progression. Her studies provide critical insights into pyroptosis, mitochondrial dynamics, and gene coexpression networks to enhance anti-tumor immunity and antiviral defense. Through high-impact publications, she contributes to advancing immunotherapy and precision medicine for infectious diseases and cancer treatment. ๐โจ
Publication Top Notes
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Enhancer decommissioning by MLL4 ablation elicits dsRNA-interferon signaling and GSDMD-mediated pyroptosis to potentiate anti-tumor immunity.
- Year: 2022
- Journal: Nature Communications
- Impact Factor: 16.6
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DDAH2 suppresses RLR-MAVSโmediated innate antiviral immunity by stimulating nitric oxide-activated, Drp1-induced mitochondrial fission.
- Year: 2021
- Journal: Science Signaling
- Impact Factor: 7.8
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Transcriptional landscape of cholangiocarcinoma revealed by weighted gene coexpression network analysis.
- Year: 2020
- Journal: Briefings in Bioinformatics
- Impact Factor: 9.5
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The otubain YOD1 suppresses aggregation and activation of the signaling adaptor MAVS through Lys63-linked deubiquitination.
- Year: 2019
- Journal: Journal of Immunology
- Impact Factor: 4.4