Prof. Hu Xiong | Analytical Chemistry | Best Researcher Award

Prof. Hu Xiong, Nankai University, China

Prof. Hu Xiong is a leading chemist at Nankai University, serving in the Research Center for Analytical Sciences. His research focuses on the design of NIR fluorescent probes and lipid nanoparticles for cancer imaging and precision drug delivery. A recipient of the Excellent Young Scholars Award and multiple NSFC grants, he has published in Angewandte, JACS, Nano Letters, and more. With a strong record of mentorship, he has supervised impactful Ph.D. work on bioimaging and nanomedicine. He is also a youth editorial board member and an active reviewer for top-tier journals.

Publication Profile

Scopus

🎓 Academic Background

Prof. Hu Xiong holds a strong foundation in chemistry, beginning with his B.S. degree from the Department of Chemistry at Zhengzhou University, Henan, China (2005–2009). He then pursued his Ph.D. in Organic Chemistry at the prestigious State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, CAS (2009–2014). His doctoral research was guided by renowned scholars Prof. Yong Tang and Prof. Zuowei Xie. This academic journey laid the groundwork for his expertise in organometallic chemistry and advanced research contributions in the field.

👨‍🏫 Academic Career

Prof. Hu Xiong began his academic career as a Postdoctoral Associate at the Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, USA (2014–2018), where he worked alongside Prof. Daniel J. Siegwart on cutting-edge biochemical research. In December 2018, he returned to China and assumed the role of Professor at the Research Center for Analytical Sciences, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Nankai University, Tianjin. His academic journey reflects a commitment to innovation and international collaboration in the fields of biosensing, molecular recognition, and analytical sciences

🏆 Awards and Honors

Prof. Hu Xiong has been recognized for his exceptional contributions to science and education. In 2019, he was honored with the prestigious “131 Innovative Talent Development Program” award , highlighting his innovative research capabilities. In 2023, his dedication to mentoring was acknowledged when he received the “Outstanding Master’s Thesis Supervisor at Nankai University” award 🎓. Most recently, in 2024, Prof. Hu Xiong was awarded The National Science Fund for Excellent Young Scholars , a testament to his significant impact and promise in advancing scientific research in China

📚 Teaching Responsibilities

Prof. Hu Xiong is actively engaged in teaching both undergraduate and graduate students. He teaches “Quantitative Chemical Analysis” to undergraduates, dedicating 34 class hours per semester to ensure a solid foundation in analytical chemistry. For graduate students, he offers “Graduate Research Skills Training”, providing 51 class hours per semester focused on developing advanced research techniques and critical scientific skills. Through these courses, Prof. Hu Xiong supports the academic growth and professional development of students at different levels, fostering the next generation of talented chemists and researchers

Research Focus

Prof. Hu Xiong’s research primarily focuses on the design and development of advanced near-infrared (NIR) fluorescent probes and biodegradable lipids for bioimaging and targeted drug delivery applications. His work involves creating activatable fluorescent probes for high-contrast in vivo imaging of diseases such as cancer, inflammatory bowel disease, and liver injury, emphasizing precise diagnostics and therapy guidance. Additionally, he innovates in mRNA delivery systems and phototheranostics for cancer treatment. His interdisciplinary research combines organic chemistry, nanotechnology, and molecular biology to advance non-invasive medical imaging and targeted therapeutics for clinical applications

Publication Top Notes

• Access to Diverse Activatable Heptamethine Cyanine Probes with Low Intrinsic Fluorescence via 5-exo-trig Cyclization Strategy for High-Contrast Bioimaging In Vivo
  📅 2025

• Crown-Like Biodegradable Lipids Enable Lung-Selective mRNA Delivery and Dual-Modal Tumor Imaging In Vivo
  📅 2024

• Fast-Responsive HClO-Activated Near-Infrared Fluorescent Probe for In Vivo Diagnosis of Inflammatory Bowel Disease and Ex Vivo Optical Fecal Analysis
  📅 2024

• Electron-Withdrawing Substituents Enhance Type-I PDT and NIR-II Fluorescence of BODIPY J-aggregates for Bioimaging and Cancer Therapy
  📅 2024

• Diagnosis of Non-alcoholic Fatty Liver Disease via a H2S-responsive Bioluminescent Probe Combined with Firefly Luciferase mRNA Delivery
  📅 2024

• Visualization of Endogenous Hypochlorite in Drug-induced Liver Injury Mice via a Bioluminescent Probe Combined with Firefly Luciferase mRNA-loaded Lipid Nanoparticles
  📅 2024

• High Spatiotemporal Tracking of Intestinal Peristalsis and Bowel Disease via In Situ Generated NIR-II Cyanine-Albumin Complex
  📅 2024

• Acid-promoted fluorescent probe for monitoring endogenous methylglyoxal in tumors and gastritis
  📅 2024

• Electron-Withdrawing Substituents Allow Boosted NIR-II Fluorescence in J-Type Aggregates for Bioimaging and Information Encryption
  📅 2023

• Modular Design of Biodegradable Ionizable Lipids for Improved mRNA Delivery and Precise Cancer Metastasis Delineation In Vivo
  📅 2023

• “Dual-Key-and-Lock” NIR-II NSCyanines Enable High-Contrast Activatable Phototheranostics in Extrahepatic Diseases
  📅 2023

• Non-Solvatochromic Cell Membrane-Targeted NIR Fluorescent Probe for Visualization of Polarity Abnormality in Drug-Induced Liver Injury Mice
  📅 2023

• BOIMPY-based NIR-II Fluorophore with High Brightness and Long Absorption beyond 1000 nm for In Vivo Bioimaging: Synergistic Steric Regulation Strategy
  📅 2022

• Three Birds with One Stone: Acceptor Engineering of Hemicyanine Dye with NIR-II Emission for Synergistic Photodynamic and Photothermal Anticancer Therapy
  📅 2022

• Bichromatic Imaging with Hemicyanine Fluorophores Enable Simultaneous Visualization of Non-alcoholic Fatty Liver Disease and Metastatic Intestinal Cancer
  📅 2022

• H2O2-activated NIR-II Fluorescent Probe with Large Stokes Shift for High-contrast Imaging in Drug-induced Liver Injury Mice
  📅 2022

• An Acid-Enhanced OFF-ON Fluorescent Probe for the Detection of Hypochlorous Acid in Rheumatoid Arthritis
  📅 2022

• Modular Design of High-Brightness pH-Activatable Near-Infrared BODIPY Probes for Noninvasive Fluorescence Detection of Deep-Seated Early Breast Cancer Bone Metastasis
  📅 2021

• A Fast-Responsive OFF-ON Near-Infrared-II Fluorescent Probe for in Vivo Detection of Hypochlorous Acid in Rheumatoid Arthritis
  📅 2021

• Development of pH-activatable fluorescent probes for rapid visualization of metastatic tumours and fluorescence-guided surgery via topical spraying
  📅 2021